Actively Recruiting
Lutein, Zeaxathin, and Fish Oil Supplementation
Led by Texas A&M University · Updated on 2025-09-30
80
Participants Needed
1
Research Sites
116 weeks
Total Duration
On this page
Sponsors
T
Texas A&M University
Lead Sponsor
A
Allen Foundation Inc.
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn the impact of lutein, zeaxanthin, and fish oil (LZF) supplementation in healthy adults. The main question it aims to answer is: Will supplementation with LZF improve macular pigment optical density (MPOD), cognitive performance and bone mass compared to controls after six months? Subjects with an MPOD \<.43 will significantly improve MPOD after 6-months of LZF supplementation. Consuming a LZFO supplement for 6-months will improve visual cognitive performance. Consuming a LZFO supplement for 6-months will improve bone density. Participants will be asked to take either a LZF supplement or placebo daily for 6 months.
CONDITIONS
Official Title
Lutein, Zeaxathin, and Fish Oil Supplementation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Macular pigment optical density (MPOD) less than 0.43
- Self-reported best-corrected vision of 20/40 or better in each eye
- Body mass index (BMI) between 18.5 and 30
- Meets inclusion criteria on the preliminary participant questionnaire
- Age between 18 and 45 years
You will not qualify if you...
- Allergy to lutein, zeaxanthin, or fish oil
- Taking supplements with more than 6 mg lutein and/or more than 2 mg zeaxanthin for over two months before study starts
- Macular pigment optical density (MPOD) greater than 0.43
- Self-reported history of vertigo, diabetic retinopathy, retinitis pigmentosa, optic neuropathy, retinal vascular occlusions, or strabismus
- Autoimmune disorders related to visual health
- Currently pregnant or trying to become pregnant
- History of concussion
- Vegan (due to gelatin in placebo)
- Taking neuroactive medications such as Ritalin, Adderall, antidepressants, etc.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Gilchrist Building
College Station, Texas, United States, 77843
Actively Recruiting
Research Team
K
Karen M Beathard, PhD
CONTACT
S
Steven E Riechman, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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