Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04498221

Lymphatic Mapping Of Oropharyngeal Cancer

Led by University College, London · Updated on 2024-09-19

150

Participants Needed

2

Research Sites

234 weeks

Total Duration

On this page

Sponsors

U

University College, London

Lead Sponsor

N

National Institute for Health Research, United Kingdom

Collaborating Sponsor

AI-Summary

What this Trial Is About

A multi-centre validation study to evaluate whether a new imaging and surgical protocol would work as well as the current gold standard in identifying sentinel nodes in patients with oropharyngeal cancer.

CONDITIONS

Official Title

Lymphatic Mapping Of Oropharyngeal Cancer

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 or over
  • New diagnosis of oropharyngeal cancer including all anatomical subsites and HPV status
  • Unilateral metastatic lymph nodes matching AJCC TNM8 staging N1-N2b for P16 negative or N1 for P16 positive patients
Not Eligible

You will not qualify if you...

  • Suspicious bilateral lymph nodes on imaging
  • Previous radiotherapy or surgery to the neck
  • Second primary oropharyngeal tumors
  • Presence of distant metastasis such as in lung or bone
  • Pregnancy or lactation
  • Inability to give informed consent
  • Allergy to lymphatic tracer substances

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

St George's University Hospitals NHS Foundation Trust

London, United Kingdom, SW17 0QT

Actively Recruiting

2

University College Hospital

London, United Kingdom

Actively Recruiting

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Research Team

T

Trial Manager

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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