Actively Recruiting
Lymphedema Prevention Through Immediate Lymphatic Reconstruction (LILY) Trial.
Led by M.D. Anderson Cancer Center · Updated on 2026-02-19
50
Participants Needed
1
Research Sites
253 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To learn if reconstruction of the lymphatic system at the time of axillary lymphadenectomy can reduce the risk of developing lymphedema.
CONDITIONS
Official Title
Lymphedema Prevention Through Immediate Lymphatic Reconstruction (LILY) Trial.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with inflammatory breast cancer (IBC)
- Scheduled for Immediate Lymphatic Reconstruction (ILR) or Prophylactic Lymphovenous Bypass (pLVB) during axillary lymphadenectomy
- Willing and able to follow the study protocol and attend all study visits
- Female, at least 18 years old, and able to provide consent
- If able to become pregnant, must have a negative urine pregnancy test within 36 hours before study procedure and agree to use contraception for one month after
You will not qualify if you...
- Pregnant or breastfeeding
- Known or suspected allergy to iodine or indocyanine green (ICG)
- Unable to stay still for one hour
- Active cellulitis infection
- Diagnosed with lymphedema before surgery
- Undergoing lymphadenectomy on both sides (bilateral ALND)
- Needing immediate chest wall reconstruction with flap surgery or having had preoperative radiation therapy
- Body mass index (BMI) over 45 kg/m2
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
MD Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
S
Sara Hull, MHA, BA, BSN, RN, CCRP
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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