Actively Recruiting

Phase Not Applicable
Age: 18Years - 64Years
All Genders
NCT06350201

Machine Learning-based Classification of Symptom Clusters and Online CBT

Led by Wuhan Mental Health Centre · Updated on 2026-05-12

380

Participants Needed

1

Research Sites

65 weeks

Total Duration

On this page

Sponsors

W

Wuhan Mental Health Centre

Lead Sponsor

N

National Natural Science Foundation of China

Collaborating Sponsor

AI-Summary

What this Trial Is About

To breakthrough the bottleneck identified, we will conduct a cross-sectional study to develop a symptom clustering model for depression and anxiety. A wide range of statistical methods as well as machine learning approaches were explored, and a cohesive hierarchical clustering algorithm will be used. After developing the model, a symptom-matched intervention program based on problem solving therapy will be formulated. We are supposed to examine whether its use for personalizing symptom-matched psychological treatment can lead to improved patient outcomes, compared with usual care. This project is expected to provide a new and precise method for the emotion management, which will provide a standardized intervention pathway combining screening with treatment for the management of depression symptom and anxiety symptom. A preciser intervention matched to individual symptoms may provide important insight in improving patient outcome as well as a standardized mood management pathway targeting to the early detection and intervention for community residents.

CONDITIONS

Official Title

Machine Learning-based Classification of Symptom Clusters and Online CBT

Who Can Participate

Age: 18Years - 64Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged between 18 and 64 years
  • PHQ-9 score of 10 or higher and/or GAD-7 score of 8 or higher at baseline assessment
Not Eligible

You will not qualify if you...

  • Currently receiving psychological therapy for any mental health issue
  • Acutely suicidal or attempted suicide in the past 2 months as indicated by PHQ-9 item 9
  • Diagnosed with bipolar disorder, psychosis, or experiencing psychotic symptoms
  • Dependent on alcohol or drugs
  • Living with an unstable or acute medical illness that would interfere with trial participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Renmin Hospital of Wuhan University

Wuhan, China

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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