Evaluating Magic Angle Directional Imaging MADI Using a New MRI Scanner for Diagnosing Anterior Cruciate Ligament Injuries in Adults Aged 18 to 65

What this Trial Is About

Researchers are investigating a new Magnetic Resonance Imaging MRI scanner designed to provide better images of tissues like ligaments, tendons, and cartilage. This study focuses on using Magic Angle Direction Imaging MADI to examine the anterior cruciate ligament ACL in the knee. The goal is to see if this technique can give more detailed information about collagen fiber structures to help diagnose ACL injuries more accurately compared to conventional MRI. The study uses a novel prototype MRI scanner that can move around the patient to capture images from different angles. Patients with diagnosed ACL tears will undergo scans in this MA-MRI scanner, which is located at Imperial College London. The scanning visit takes about 1.5 hours, with the imaging itself lasting around an hour. Patients will be comfortably seated and their knee positioned carefully during the scan. Researchers will analyze the images qualitatively and quantitatively to assess ligament structure and compare results with conventional MRI. Participants will provide informed consent before scanning and may be reimbursed for travel expenses. After the scan, researchers will review the images and may share additional findings with the patients clinical team. One year after the scan, patients will be contacted to collect any new clinical information or imaging related to their injury. The study aims to measure the reproducibility of the Magic Angle MRI before and 12 months after surgery, with ongoing safety and efficacy monitoring throughout the study period.

Magic Angle Direction Imaging (MADI) ACL Study