Actively Recruiting
Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty
Led by University of Miami · Updated on 2026-04-23
64
Participants Needed
1
Research Sites
62 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study team is conducting a study to see if Magnesium-L-Threonate (MgT) can help improve how well participants sleep and reduce pain after total joint replacement surgery
CONDITIONS
Official Title
Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing primary total knee or hip arthroplasty at the University of Miami Hospital
- Patients > 18 years of age
- Subjects must be capable of providing informed consent
- English or Spanish-speaking
You will not qualify if you...
- Previous total joint arthroplasty at the surgical site
- History of sleeping disorders, including narcolepsy, sleep apnea, insomnia, parasomnias, and restless leg syndrome
- History of Complex Regional Pain Syndrome in ipsilateral extremity
- History of demyelinating disorder or neurologic deficit in the affected extremity
- History of psychiatric disorders that could impact sleep, such as untreated depression, bipolar disorder, or schizophrenia
- Participants taking medications known to cause significant sedation or insomnia
- Pregnant or breastfeeding
- Being treated for a diagnosis other than primary osteoarthritis (e.g. pelvic/femur fracture)
- Patients with known substance use disorder within 6 months of surgery
- Liver Failure, via clinical diagnosis or international normalized ratio greater than 1.5 or Prothrombin time greater than 40
- Chronic Kidney Disease or glomerular filtration rate less than 30 mL/min
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Miami Hospital
Miami, Florida, United States, 33136
Actively Recruiting
Research Team
V
Victor H Hernandez, MD
CONTACT
J
Jonathan Stern, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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