Actively Recruiting

Phase 2
Phase 3
Age: 18Years +
All Genders
NCT06956950

Magnesium Sulfate in Addition to Bupivacaine in Ultrasound-guided Transmuscular Quadratus Lumborum Block for Post-Operative Analgesia After Total Hip Arthroplasty

Led by Tanta University · Updated on 2025-05-11

70

Participants Needed

1

Research Sites

26 weeks

Total Duration

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AI-Summary

What this Trial Is About

The aim of this clinical trial is to evaluate the efficacy of adding magnesium sulfate to bupivacaine in ultrasound-guided transmuscular quadratus lumborum block for postoperative analgesia in adult patients underdoing hip arthroplasty. The main questions it aims to answer are: * Does Magnesium sulphate lower Pain score (VAS) postoperatively. * Does Magnesium sulphate lowerTotal opioid consumption postoperatively. and What side effects do participants have when taking Magnesium sulphate? Researchers will compare Magnesium sulphate to a placebo (a look-alike substance that contains no drug) to see if Magnesium sulphate works to lower pain score. Participants will: * Take with have ultrasound-guided transmuscular quadratus lumborum block after surgery using bupivacaine with Magnesium sulphate or with placebo * Followed up 48 hours postoperatively to monitor pain score or any reported side effect.

CONDITIONS

Official Title

Magnesium Sulfate in Addition to Bupivacaine in Ultrasound-guided Transmuscular Quadratus Lumborum Block for Post-Operative Analgesia After Total Hip Arthroplasty

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 25 18 years
  • American Society of Anesthesiology (ASA) class I-III
  • Undergoing hip arthroplasty
Not Eligible

You will not qualify if you...

  • Patient refusal
  • Body mass index (BMI) > 40 Kg/m2
  • Allergy to local anesthetics or magnesium sulphate
  • Coexisting coagulopathy
  • Local infection at puncture site
  • Severe renal impairment (eGFR < 30 ml/min)

AI-Screening

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Trial Site Locations

Total: 1 location

1

Faculty of medicine

Tanta, El-Gharbia, Egypt, 31527

Actively Recruiting

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Research Team

M

Mostafa Mohammad Abdelsattar Elbagoury, MD

CONTACT

D

Dina Abdalla Elesawy Amer, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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