Actively Recruiting

Phase Not Applicable
Age: 18Years - 99Years
All Genders
NCT04868994

Magnetic Imaging for Diagnostic of Amyotrophic Lateral Sclerosis

Led by University Hospital, Toulouse · Updated on 2024-08-02

50

Participants Needed

1

Research Sites

182 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Nearly 60% of Amyotrophic Lateral Sclerosis (ALS) patients have a low level of diagnostic certainty (possible, probable) at the time of diagnosis. In the absence of biomarkers, this diagnosis is based, among other things, on the demonstration of the diffusion of signs of denervation by electroneuromyography (ENMG). The objective of this study is to improve the earliness and the level of diagnostic certainty by better demonstrating the diffusion of the denervation process by whole body muscular MRI.

CONDITIONS

Official Title

Magnetic Imaging for Diagnostic of Amyotrophic Lateral Sclerosis

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed consent form from the patient
  • Suspected ALS defined by Awaji Shima criteria (possible, probable, defined)
  • Clinical evidence of upper motor neuron involvement
  • Electrophysiologic evidence of lower motor neuron involvement
Not Eligible

You will not qualify if you...

  • Unable to give informed consent
  • Contraindication to MRI
  • Respiratory failure preventing lying flat in the scanner
  • Under judicial protection or another protective regime
  • Female who is pregnant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Pascal CINTAS

Toulouse, France, 31000

Actively Recruiting

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Research Team

P

Pascal CINTAS, MD PHD

CONTACT

A

Anne Cecile Coville

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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