Actively Recruiting
Magnetic Marker Localization for Occult Breast Cancer and Target Axillary Dissection in Node-positive Breast Cancer Post-neoadjuvant Chemotherapy
Led by The University of Hong Kong · Updated on 2022-06-22
30
Participants Needed
1
Research Sites
428 weeks
Total Duration
On this page
Sponsors
T
The University of Hong Kong
Lead Sponsor
E
Endomagnetics Ltd.
Collaborating Sponsor
AI-Summary
What this Trial Is About
The use of neoadjuvant chemotherapy in breast cancer is expanding in the recent decade. Patients with good response to neoadjuvant chemotherapy could benefit from de-escalation of breast and axilla operation. However, breast tumor and involved axillary lymph node should be marked before the commencement of chemotherapy. This could facilitate subsequent operative planning and intraoperative assessment of disease response. This study aims to evaluate the feasibility of magnetic marker localization for non-palpable breast cancer and targeted axillary dissection in patients with node-positive breast cancer following neoadjuvant therapy
CONDITIONS
Official Title
Magnetic Marker Localization for Occult Breast Cancer and Target Axillary Dissection in Node-positive Breast Cancer Post-neoadjuvant Chemotherapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with cT1-3N1 invasive ductal carcinoma planned for neoadjuvant chemotherapy and/or target therapy
- Mentally competent to give informed consent
- Agreed to undergo curative surgery after chemotherapy and interested in breast conservative surgery and targeted axillary dissection
- Radiologically confirmed 1-3 ipsilateral axillary lymph node metastases by cytology or biopsy
You will not qualify if you...
- Presence of distant metastasis, inflammatory breast cancer, or multi-centric breast cancer
- History of previous surgery or radiation to the same side axilla
- Hypersensitivity to dextran compounds or iron
- Iron overload disease
- Pregnant or breastfeeding
- Presence of pacemaker or other implantable metallic devices in the chest wall or shoulder prosthesis
- Mentally incompetent patients
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Hong Kong
Hong Kong, Hong Kong
Actively Recruiting
Research Team
C
Chi Mei Vivian Man, FCSHK, FRCSEd
CONTACT
C
Christine Chan, Miss
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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