Actively Recruiting
Magnetic Resonance Analysis of Neural Inflammatory Factors and External Stimulation
Led by University of New Mexico · Updated on 2025-07-15
60
Participants Needed
1
Research Sites
207 weeks
Total Duration
On this page
Sponsors
U
University of New Mexico
Lead Sponsor
T
The Mind Research Network
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to test whether a type of rapid outpatient brain stimulation that uses magnetic fields, called accelerated intermittent theta burst stimulation (iTBS), can treat symptoms such as brain fog, depression, and anxiety in patients with Long COVID. The main questions it aims to answer are: * Is iTBS effective and feasible for reducing Long COVID symptoms? We will measure these symptoms using the Symptom Burden Questionnaire. * Are there changes in inflammatory brain chemicals associated with treatment with iTBS? We will be looking at levels of choline in the brain, which is thought to be related to inflammation. Researchers will compare sham versus active forms of iTBS to see if the active group has greater improvement in symptoms. Participants will complete symptom surveys, cognitive tests, and magnetic resonance imaging scans at the beginning, middle, and end of treatment.
CONDITIONS
Official Title
Magnetic Resonance Analysis of Neural Inflammatory Factors and External Stimulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 to 80 years
- Documented diagnosis of post-acute sequelae of COVID-19 (PASC) with ongoing symptoms shown by a score of 12 on the NIH RECOVER Symptom List
- Experiencing brain fog or cognitive difficulties as one of the ongoing symptoms
- Fluent in English
- If taking psychotropic medications, doses have been stable for the past month
You will not qualify if you...
- History of other neurological diseases or seizures
- History of psychotic disorders such as schizophrenia or bipolar disorder
- Ongoing substance or alcohol dependence
- Presence of any implanted electrical device like a pacemaker
- Recent medical hospitalization within four weeks
- Any condition preventing completion of the study protocol
- Appointment of a legal representative
- Ongoing litigation related to medical diagnosis or disability
- Contraindications to MRI
- Membership in vulnerable populations including minors, pregnant women, and prisoners
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of New Mexico Health Science Center
Albuquerque, New Mexico, United States, 87106
Actively Recruiting
Research Team
C
Crystal Garcia
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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