Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
Healthy Volunteers
NCT05990244

Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion

Led by Shengjing Hospital · Updated on 2025-12-02

100

Participants Needed

1

Research Sites

547 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

this study will investigate the relationship between tumor stiffness and adhesion in gliomas using MRE. By utilizing preoperative MRE and Intraoperative neuronavigation, followed by comprehensive molecular pathology analysis, we aim to explore the correlation of tumor stiffness and adhesion with molecular and genetic characteristics of gliomas. Additionally, the predictive value of MRE in terms of pathological staging and prognosis will be determined. This research may pave the way for improved clinical decision-making, personalized treatment approaches, and more accurate clinical trials for glioma patients.

CONDITIONS

Official Title

Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age older than 18 years
  • Karnofsky performance status higher than 60
  • Signed written informed consent
  • Magnetic Resonance Elastography (MRE) performed within one week before surgery
  • Tumor diameter greater than 2 cm
Not Eligible

You will not qualify if you...

  • Previous treatment for glioma
  • Inability to complete MRE due to intolerance such as vibration discomfort or claustrophobia
  • Completed MRE with poor image quality due to motion artifacts or inadequate wave amplitude
  • Failure to proceed with surgery after MRE
  • Missing IDH genetic results

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Shengjing Hospital

Shenyang, Liaoning, China, 110000

Actively Recruiting

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Research Team

Y

Yu Shi, MD

CONTACT

Y

Yu Zeng, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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