Actively Recruiting

Age: 18Years +
All Genders
NCT07486219

Magnetic Resonance Imaging of the Lung: Oncological Applications

Led by Fondazione IRCCS Policlinico San Matteo di Pavia · Updated on 2026-03-20

50

Participants Needed

1

Research Sites

324 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Lung neoplasms are characterized by a complex interaction between tumor cells and a variety of resident and infiltrating host elements, secreted factors, and extracellular matrix proteins, collectively referred to as the microenvironment. Nowadays, in the setting of lung cancer, and in particular non-small cell lung cancer (NSCLC), the evaluation of microenvironment characteristics can only be performed by a pathologist and only on histological material. By combining different MRI parameters, it may be possible to create a specific imaging "signature" for the three different immune phenotypes and thus be able to make a distinction based on MRI examination.

CONDITIONS

Official Title

Magnetic Resonance Imaging of the Lung: Oncological Applications

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Primary non-small cell lung cancer of the lung with tumor size T1c or larger according to TNM 8th edition
  • Biopsy of the primary tumor adequate for PDL-1 quantification
  • Staging CT scan showing uncertain lymph node involvement and definite distant metastasis
Not Eligible

You will not qualify if you...

  • Absolute contraindications to magnetic resonance imaging or to gadolinium-based contrast agents

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fondazione IRCCS Policlinico San Matteo

Pavia, Italy, 27100

Actively Recruiting

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Research Team

C

Chandra Bortolotto

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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