Actively Recruiting
Magnetic Resonance Imaging in Metabolic Diseases
Led by University of Ulm · Updated on 2026-02-13
126
Participants Needed
1
Research Sites
251 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to leverage structural, functional, and metabolic magnetic resonance imaging (MRI) of the brain to identify imaging features that correlate with clinical parameters. It is hypothesized that individuals with metabolic diseases exhibit distinct functional and structural brain differences compared to healthy controls. These differences may evolve over time due to changes in whole-body metabolism or body weight, influenced by factors such as the natural progression of the disease or therapeutic interventions. Additionally, potential brain changes may correlate with body composition metrics, such as the fat content of specific body compartments. This is a prospective, single-center study conducted at Ulm University Hospital, designed to track the clinical and imaging histories of patients with metabolic diseases and compare them to healthy individuals. Eligible participants include adults (aged 18 and older) capable of providing informed consent. Recruitment will occur through routine clinical care or existing research studies. To provide a comprehensive understanding, the study will include both cross-sectional analyses and longitudinal follow-up of participants, integrating repeated assessments during routine medical visits.
CONDITIONS
Official Title
Magnetic Resonance Imaging in Metabolic Diseases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with metabolic diseases or healthy control participants without metabolic diseases
- Adults aged 18 years or older
- Able to provide written informed consent
You will not qualify if you...
- History of traumatic brain injuries
- Preterm birth (before 34th week of pregnancy)
- History of brain surgery
- Structural brain changes such as tumors or congenital abnormalities
- Neurological developmental disorders including autism spectrum disorders, learning disabilities, or intellectual disability
- Epilepsy
- Drug addiction
- Severe neurological or psychiatric disorders such as schizophrenia
- Pregnancy
- Acute clinically relevant inflammatory diseases
- Acute systemic or local infections
- Severe or unclear diseases as judged by the principal investigator
- Pre-existing intellectual impairment
- Significant difficulties in understanding language
- Absence of written consent
- General MRI exclusion criteria like having a pacemaker, neurostimulator, or cochlear implant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital Ulm
Ulm, Germany, 89081
Actively Recruiting
Research Team
M
Martin Heni, Prof. Dr. med.
CONTACT
N
Nico Sollmann, PD Dr. Dr. med.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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