Actively Recruiting
Magnetic Resonance Imaging (MRI) and Eye-tracking Predictive Markers of Cognitive Ageing.
Led by University Hospital, Toulouse · Updated on 2025-12-22
100
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research proposes to investigate physiological and cognitive markers of locus coeruleus (LC) neuronal integrity and function in cognitively-healthy participants over 60 years old. The locus coeruleus is a brainstem nucleus, sole source of noradrenaline for the brain. Tau pathology appears in neurons of this nucleus, which may induce initial cognitive changes. The study aims at relating locus coeruleus markers, assessed with MRI and eye-tracking techniques, with cognitive function.
CONDITIONS
Official Title
Magnetic Resonance Imaging (MRI) and Eye-tracking Predictive Markers of Cognitive Ageing.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participant in the INSPIRE cohort
- Mini-Mental State Examination score of 27 or higher out of 30
- Access to internet at participant's or relative's home and regular internet use
- Signed informed consent
- Affiliated with a social security scheme
You will not qualify if you...
- Any contraindications to MRI exam such as pacemaker, cardiac defibrillator, electrically or magnetically activated implants, haemostatic clips, orthopedic implants, or claustrophobia
- Eye diseases affecting eye-tracking measures including glaucoma, age-related macular degeneration, or unoperated cataract
- Neurological or psychiatric conditions
- Being under guardianship or curatorship
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital
Toulouse, France, 31059
Actively Recruiting
Research Team
P
Pierre PAYOUX, MD
CONTACT
F
Florence REMY, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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