Actively Recruiting
Magnetic Resonance Imaging Study on Young and Middle-aged Patients With Cervical Spondylotic Pain
Led by First Affiliated Hospital Xi'an Jiaotong University · Updated on 2024-02-26
80
Participants Needed
1
Research Sites
207 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Cervical and shoulder pain in young adults is commonly caused by intervertebral disc degeneration, bulge or herniation. Disc degeneration includes the synthetic and degradative imbalance of myxoid matrix, degeneration of annulus collagen, and decrease of water content in nucleus pulposus. A few patients with cervical degeneration had moderate to severe pain, but there are no obvious abnormalities in the shape and signal of the disc with routine MRI, which may be related to the early discal degeneration. In most cases, the pain could be relieved by non-surgical treatment due to mild decreased proteoglycan and slight abnormality of water diffusion, but these changes cannot be clearly demonstrated by routine MRI. Therefore, it is necessary to rely on sensitive MRI techniques to reflect the abnormal microstructure in the nucleus pulposus and annulus fibrosus, so as to assist the early detection of the main reason in patients with neck and shoulder pain and the evaluation of the efficacy of treatment.
CONDITIONS
Official Title
Magnetic Resonance Imaging Study on Young and Middle-aged Patients With Cervical Spondylotic Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Neck and shoulder pain, with or without upper limb pain and numbness
- Symptoms lasting longer than 2 months
- Pain intensity with a visual analogue score of 3 or higher
- Cervical MRI showing disc degeneration, bulge, or protrusion
- Planned to undergo non-surgical treatments like maxillary occipital traction or massage
You will not qualify if you...
- Severe trauma or surgery in the neck and shoulder area
- X-ray or CT showing severe cervical spine overgrowth, infection, tumors, rheumatic diseases, or disc calcification
- Cervical MRI showing serious organic lesions like spinal cord inflammation, tumors, or syringomyelia
- Chronic pain in other body regions
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China, 710061
Actively Recruiting
Research Team
Y
Yuan Wang, M.D.
CONTACT
D
Dan Li, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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