Actively Recruiting
Magnetic Resonance Spectroscopy Studies of Cardiac Muscle Metabolism
Led by Johns Hopkins University · Updated on 2026-03-09
500
Participants Needed
1
Research Sites
2117 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins University
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The metabolism of the heart provides the chemical energy needed to fuel ongoing normal heart contraction. Magnetic resonance spectroscopy is a technique used in a MRI scanner that can be used to measure and study heart metabolism directly but without blood sampling or obtaining tissue biopsies. One of the hypotheses this study aims to investigate is whether energy metabolism is reduced in heart failure and whether that contributes to the poor heart function.
CONDITIONS
Official Title
Magnetic Resonance Spectroscopy Studies of Cardiac Muscle Metabolism
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years
- Healthy subjects with no history of heart disease
- Participants with dilated cardiomyopathy and history of heart failure with ejection fraction less than 40%
- Participants with left ventricular hypertrophy defined by wall thickness greater than 1.2 cm
- Participants with coronary artery disease with more than 50% coronary lesion or positive stress test
You will not qualify if you...
- Contraindication to MRI
AI-Screening
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Trial Site Locations
Total: 1 location
1
Johns Hopkins Medical Institutions
Baltimore, Maryland, United States, 21205
Actively Recruiting
Research Team
R
Robert G. Weiss, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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