Actively Recruiting
Magnetocardiography in the Accurate Identification of Severe Coronary Lesions and Myocardial Necrosis
Led by Qilu Hospital of Shandong University · Updated on 2024-08-22
430
Participants Needed
1
Research Sites
135 weeks
Total Duration
On this page
Sponsors
Q
Qilu Hospital of Shandong University
Lead Sponsor
S
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Magnetocardiography (MCG) is a promising noninvasive and accurate method for detecting myocardial ischemia. Although progress has been made in this area, there is a lack of studies using up-to-date examination instruments for the calibration of MCG analysis. This is a prospective single-center study aiming to build accurate analytical models of MCG to detect coronary lesions and myocardial necrosis. Coronary lesions are measured by coronary angiography (CAG) or coronary CTA, and are defined by both the stenosis degree and the computer-simulated fraction flow reserve. Myocardial necrosis is examined and quantified by cardiac MR. Healthy volunteers, chest pain patients who will receive CAG or CTA examination, and patients with acute myocardial infarction will be enrolled in this study.
CONDITIONS
Official Title
Magnetocardiography in the Accurate Identification of Severe Coronary Lesions and Myocardial Necrosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 79 years old
- For healthy volunteers: no history of cardiovascular disease or risk factors; for those over 65, controlled hypertension or hyperlipidemia with no significant heart abnormalities
- Normal electrocardiogram and cardiac ultrasound within the past year (mild valve leakage allowed)
- Signed informed consent
- For chest pain patients: diagnosed or suspected stable or unstable angina, or myocardial infarction types, planning to receive CAG or coronary CTA
- For acute myocardial infarction patients: diagnosed with acute myocardial infarction, stable condition, and able to undergo cardiac MRI
- Signed informed consent
You will not qualify if you...
- Acute or chronic respiratory diseases
- Significant liver or kidney function abnormalities
- Endocrine disorders such as abnormal thyroid function
- Anemia or other blood diseases
- Connective tissue diseases with or without cardiac complications
- Obesity (BMI >30) or underweight (BMI <18)
- Malignant tumors
- Infectious diseases
- Trauma or physical disabilities preventing examination
- Psychological or mental illnesses such as depression
- Professional athletes
- Pregnant or breastfeeding women
- Alcohol dependence
- Inability to undergo magnetocardiography due to claustrophobia or physical impairment
- Allergy to contrast agents or metal implants preventing MRI or related tests
- Failure or inability to cooperate with study requirements
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Qilu Hospital of Shandong University
Jinan, Shandong, China, 250012
Actively Recruiting
Research Team
J
Jiaojiao Pang, Dr.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
3
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