Actively Recruiting
Maintenance Tislelizumab + Capecitabine to Treat Metastatic Colorectal Cancer
Led by Yanhong Deng · Updated on 2023-12-12
52
Participants Needed
1
Research Sites
223 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Surgery with integrated treatment for metastatic colorectal cancer (mCRC) has created a new clinical setting known as mCRC with no evidence of disease (NED). However, these patients have a high risk of developing persistent cancer. This study aimed to investigate the efficacy and safety of Tislelizumab combined with capecitabine as a maintenance treatment for patients with mCRC-NED.
CONDITIONS
Official Title
Maintenance Tislelizumab + Capecitabine to Treat Metastatic Colorectal Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 20 and 79 years
- Written informed consent provided
- Histologically or cytologically confirmed colorectal cancer
- Surgery with integrated treatment for metastatic colorectal cancer and achieved no evidence of disease (NED) status confirmed by a tumor board
- If peritoneal metastasis is present, cytoreduction surgery must achieve no visible residual tumor (CC0)
- No previous chemotherapy treatment
- Metastatic disease involves a maximum of two distant organs or regions, synchronous or metachronous
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
- Adequate blood and organ function
You will not qualify if you...
- Presence of any other active cancer
- Presence of active infections requiring antibiotic treatment
- History of active autoimmune disease needing systemic treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Gastrointestinal Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China, 510655
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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