Actively Recruiting
Mako Cementless TKA vs Mako Cemented TKA
Led by University College, London · Updated on 2026-02-20
120
Participants Needed
1
Research Sites
304 weeks
Total Duration
On this page
Sponsors
U
University College, London
Lead Sponsor
S
Stryker Nordic
Collaborating Sponsor
AI-Summary
What this Trial Is About
The overall aims of this prospective, randomised, single-blinded controlled trial are to compare functional, radiological and clinical outcomes in Mako robotic-arm assisted cementless Total Knee Arthroplasty (TKA) versus Mako robotic-arm assisted cemented TKA.
CONDITIONS
Official Title
Mako Cementless TKA vs Mako Cemented TKA
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient has symptomatic knee osteoarthritis requiring primary TKA
- Patient and surgeon agree that TKA is the most appropriate treatment
- Patient is fit for surgical intervention after surgeon and anaesthetist review
- Patient is over 18 years old at time of surgery
- Male and female patients are eligible
- Patient can give informed consent and agrees to comply with postoperative review
- Patient has enough mobility to attend follow-up clinics and have radiographs taken
You will not qualify if you...
- Patient is unsuitable for routine primary TKA, such as needing a constrained prosthesis due to ligament deficiency
- Patient has bone loss requiring augmentation
- Patient is not medically fit for surgery
- Patient requires revision surgery after failed previous osteotomy or ipsilateral TKA
- Patient has a DEXA scan T-score below -2.5
- Patient is immobile or has a neurological condition affecting musculoskeletal function
- Patient is under 18 years old at time of surgery
- Patient is unable or unwilling to sign informed consent for this study
- Patient is unable to attend follow-up visits
- Patient has a previous pathological fracture
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UCL Hospitals NHS Foundation Trust
London, United Kingdom, NW1 2PG
Actively Recruiting
Research Team
J
Jenni Tahmassebi, BSc MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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