Actively Recruiting

Phase Not Applicable
Age: 35Years - 60Years
All Genders
Healthy Volunteers
ID06762171

Evaluation of High Tibial Osteotomy With or Without Arthroscopic Partial Lateral Patellar Facetectomy for Combined Patellofemoral and Medial Compartment Knee Osteoarthritis A Comparative Randomized Study

Led by Sohag University · Updated on 2025-01-07

40

Participants Needed

1

Research Sites

100 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the outcomes of treating patients with combined patellofemoral and medial compartment knee osteoarthritis using open wedge high tibial osteotomy (OWHTO) either with or without arthroscopic partial lateral patellar facetectomy. The study involves patients aged 35 to 60 years with mild to moderate tibiofemoral osteoarthritis and anterior knee pain without lateral compartment involvement. It compares the results of these two surgical approaches to better understand their effects on knee function and pain. All patients will undergo OWHTO performed by the same surgical team using a standardized technique recommended by the AO international knee expert group. Participants will be randomly assigned to receive either OWHTO combined with arthroscopic partial lateral patellar facetectomy or OWHTO alone. The facetectomy involves arthroscopic removal of the overhanging lateral patellar facet to improve patellar mobility. The osteotomy is biplanar and stabilized with a Tomofix plate without additional bone grafts, followed by layered wound closure. Participants will be followed for two years after surgery, with evaluations at 2 weeks, 4 weeks, 6 weeks, 6 months, 1 year, and 2 years postoperatively. Assessments include the Knee injury and Osteoarthritis Outcome Score (KOOS) and the Kujala Score (Anterior Knee Pain Scale) to measure knee function and pain. Researchers will monitor recovery progress, knee mobility, and patellar tracking to assess treatment effectiveness and safety over time.

CONDITIONS

Official Title

Management of Combined Patellofemoral and Medial Compartment Knee Osteoarthritis

Who Can Participate

Age: 35Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 35 to 60 years
  • Mild to moderate tibiofemoral osteoarthritis (Kellgren-Lawrence grade I-II-III)
  • Anterior knee pain related to patellofemoral osteoarthritis
  • No involvement of the knee's lateral compartment
  • Knee range of motion of at least 120 degrees flexion
  • Body mass index (BMI) less than 30 kg/m2
  • Varus knee angle less than 10 degrees
Not Eligible

You will not qualify if you...

  • Advanced tibiofemoral osteoarthritis (Kellgren-Lawrence grade VI) requiring total knee replacement
  • Knee flexion deformity of 15 degrees or more
  • Inflammatory diseases such as rheumatoid arthritis

AI-Screening

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Trial Site Locations

Total: 1 location

1

Faculty of medicine, Sohag university

Sohag, Sohag Governorate, Egypt

Actively Recruiting

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Research Team

A

Ahmed Tarek Ahmed, Assistant lecturer

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial

Patellar height and posterior tibial slope after open- and closed-wedge high tibial osteotomy: a radiological study on 100 patients.

Hosam El-Azab, Parpakorn Glabgly, Jochen Paul...

https://pubmed.ncbi.nlm.nih.gov/20044496

Changes in clinical symptoms and functional disability in patients with coexisting patellofemoral and tibiofemoral osteoarthritis: a 1-year prospective cohort study.

Hirotaka Iijima, Naoto Fukutani, Takuya Isho...

https://pubmed.ncbi.nlm.nih.gov/28340623

Clinical Impact of Coexisting Patellofemoral Osteoarthritis in Japanese Patients With Medial Knee Osteoarthritis.

Hirotaka Iijima, Naoto Fukutani, Tomoki Aoyama...

https://pubmed.ncbi.nlm.nih.gov/26315986

Roentgenographic and clinical findings of patellofemoral osteoarthrosis. With special reference to its relationship to femorotibial osteoarthrosis and etiologic factors.

T Iwano, H Kurosawa, H Tokuyama...

https://pubmed.ncbi.nlm.nih.gov/2302884