Comparing Immediate Implant Placement, Alveolar Ridge Preservation, and Delayed Implant Placement After Tooth Extraction in the Front Teeth Area
Led by Centro Specialistico Odontoiatrico, Rome · Updated on 2023-12-12
60
Participants Needed
1
Research Sites
121 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are comparing three treatment methods for patients who need a single tooth removed from the front part of their mouth, including premolars. The study looks at immediate implant placement, alveolar ridge preservation followed by delayed implant placement, and spontaneous healing followed by delayed implant placement. The goal is to assess patient outcomes like discomfort, treatment costs, bone and soft tissue changes, and implant success over a period of up to five years.
Participants are randomly assigned to one of three groups immediate implant placement with bone substitute and soft tissue matrix along with immediate provisional prosthesis alveolar ridge preservation using bone substitute and collagen matrix, followed by implant placement with possible bone and soft tissue augmentation after four months or spontaneous healing with implant placement and possible augmentation after four months. All implants are placed prosthetically with specific materials and techniques.
Throughout the study, patients will have clinical, radiographic, and volumetric assessments at baseline, 4 months after extraction, and at 1, 3, and 5 years after receiving the final prosthesis. These evaluations will be done by clinicians not involved in the surgeries and who are unaware of the treatment groups. The main outcome measured is the need for additional bone and soft tissue augmentation during implant placement, along with long-term implant health and patient satisfaction. Maintenance visits will continue after prosthesis delivery.
CONDITIONS
Brief Title
Management of the Fresh Extraction Socket in the Aesthetic Area
Research Team
M
Marco Clementini, DDS, PhD
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match. Sign up to get personalized trial recommendations delivered to your inbox.
Need for single tooth extraction in the front area of the mouth, including premolars
Smoking no more than 10 cigarettes per day
Good gum health with bleeding on probing less than 10% and plaque control less than 20%
No symptomatic infections like acute abscesses at the extraction site
Extraction sites with less than 30% bone loss on one or more walls
Sufficient quality and quantity of native bone to secure implant stability
You will not qualify if you...
Underage or still growing patients
Autoimmune diseases, uncontrolled diabetes, or weakened immune system
Previous radiation treatment to head and neck for cancer
Pregnancy
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Treatment
Duration - Approximately 4 months for initial treatment and healing phases, with implant placement occurring after healing as applicable.
Participants undergo one of three treatment approaches after tooth extraction: immediate implant placement, alveolar ridge preservation followed by delayed implant placement after 4 months, or spontaneous healing followed by delayed implant placement after 4 months.
Several visits including the initial extraction, treatment visits, and implant placement visits over the 4-month healing period.
Follow-up
Duration - Up to 5 years after final prosthesis delivery
Participants have clinical, radiographic, aesthetic, and patient satisfaction assessments at the time of prosthesis delivery and at 1, 3, and 5 years after final prosthesis placement to monitor implant success and peri-implant health.
Visits at prosthesis delivery and follow-up visits at 1, 3, and 5 years post prosthesis.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Similar Trials
Studying the Pontic-shield Technique to Preserve Bone After Tooth Extraction Compared to Other Methods
Evaluating the Safety and Effectiveness of Customized CADCAM Dental Implants Over 36 Months
Comparing 3D-Printed and Milled Surgical Guides for Precise Dental Implant Placement A Randomized Clinical Study
Collecting and Using Data from Specialist Dental Treatments Including Dental Implants to Improve Patient Care and Outcomes
Randomized Comparison of Hydrogel-Enhanced Xenograft and Graftless Method for Maxillary Sinus Floor Augmentation
Assessing Bone Growth and Tissue Healing for Dental Implant Placement
Comparing Two Xenograft Materials for Bone Preservation After Immediate Implant Placement in the Front Upper Jaw
Comparing Soft Tissue Coverage Techniques Over Zygomatic Implants in Patients with Severe Maxilla Bone Loss Using Buccal Fat Pad and Palatal Pedicle Flap
Evaluating Early vs. Delayed Crown Placement on Nobel N1 Dental Implants
Effects on Implant Survival and Stability Over One Year
Evaluating Safety and Accuracy of Straumann Falcon Dynamic Navigation System for Dental Implant Placement in Adults with Partial Tooth Loss
Study of 3-D X-Ray Imaging After Closed Sinus Surgery Using Calcium Phosphosilicate Putty
to Prepare for Dental Implants
in Adults Ages 18 to 85
Have more questions? Get in touch with our team for quick support
Published Research Related To This Trial
The effect of immediate implant placement on alveolar ridge preservation compared to spontaneous healing after tooth extraction: Radiographic results of a randomized controlled clinical trial.
Marco Clementini, Agnese Agostinelli, Walter Castelluzzo...
Management of the extraction socket and timing of implant placement: Consensus report and clinical recommendations of group 3 of the XV European Workshop in Periodontology.
Maurizio S Tonetti, Ronald E Jung, Gustavo Avila-Ortiz...