Actively Recruiting
Management of Patients with Heart Failure At Home After Hospital Discharge
Led by University Hospital, Akershus · Updated on 2025-03-25
450
Participants Needed
2
Research Sites
182 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Akershus
Lead Sponsor
D
Drammen sykehus
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to assess whether patients with acute heart failure (HF) can achieve the same level of HF-therapies by digital follow-up at home as compared to hospital visits according to the STRONG-HF strategy. Patients admitted to hospital with acute HF will be enrolled and randomized to either follow-up at the hospital out-patient clinic or digital follow-up at home.
CONDITIONS
Official Title
Management of Patients with Heart Failure At Home After Hospital Discharge
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Hospital admission within the 72 hours prior to screening for acute heart failure
- NT-proBNP level greater than 1,500 pg/mL during hospitalization
- Systolic blood pressure at least 100 mmHg and heart rate at least 60 bpm within 24 hours before randomization
- Serum potassium level 5.0 mEq/L or lower
- Receiving no more than half the optimal dose of ACEi/ARB/ARNi or beta-blocker or MRA
- Provided written informed consent to participate in the study
You will not qualify if you...
- Age below 18 or above 85 years
- Documented intolerance to high doses of beta-blockers
- Documented intolerance to high doses of renin-angiotensin system blockers (both ACEi and ARB)
- Renal disease or estimated glomerular filtration rate below 30 mL/min/1.73m2 or history of dialysis
- Participation in another heart failure intervention or investigational drug/device study within 30 days prior to screening
- Acute heart failure event caused by a fully reversible condition unlikely to lead to chronic heart failure after discharge
- Severe non-adherence to medications
- Psychiatric or neurological disorders, cirrhosis, or active cancer with life expectancy less than 6 months
- History of heart transplant or planned ventricular assist device implantation
- Uncorrected thyroid disease, active myocarditis, or known amyloid or hypertrophic obstructive cardiomyopathy
- Inability to comply with study requirements due to comorbidities, social, financial, or compliance issues
- Low digital competency preventing use of a smartphone or tablet
- Language barriers requiring an interpreter
- Pregnant or nursing women
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Akershus University Hospital
Lørenskog, Akershus, Norway, 1478
Actively Recruiting
2
Drammen Hospital, Vestre Viken HF
Drammen, Vestre Viken, Norway, 1878
Actively Recruiting
Research Team
P
Peder L Myhre, MD, PhD
CONTACT
H
Henrik Schirmer, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
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