Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06988111

Management of Post-operative Respiratory Failure by Using NIV and High Velocity Nasal Insufflation (HVNI)

Led by Assiut University · Updated on 2026-04-30

180

Participants Needed

1

Research Sites

74 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Postoperative respiratory failure (PORF) remains a critical driver of morbidity, mortality, and incremental care costs in surgical populations. Traditional escalation often involves invasive mechanical ventilation, which is associated with ventilator-associated pneumonia (VAP), prolonged intensive care unit (ICU) stays, and increased resource burden.

CONDITIONS

Official Title

Management of Post-operative Respiratory Failure by Using NIV and High Velocity Nasal Insufflation (HVNI)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age above 18 years
  • Within 48 hours after major surgery
  • PAO2/FIO2 less than 200
  • Signs of respiratory distress and respiratory rate more than 25 cycles per minute
Not Eligible

You will not qualify if you...

  • Age below 18 years
  • Pregnant ladies
  • Orofacial trauma or burns
  • Active gastrointestinal bleeding

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Assuit Univeristy

Asyut, Assuit, Egypt, 71515

Actively Recruiting

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Research Team

A

Ahmad M. Shaddad, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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Management of Post-operative Respiratory Failure by Using NIV and High Velocity Nasal Insufflation (HVNI) | DecenTrialz