Actively Recruiting

Phase Not Applicable
Age: 18Years - 40Years
All Genders
NCT06553950

Mandibular Splint vs Botox Injection in Lateral Pterygoid on Cervical Muscle Activity in Patients With Temporomandibular Disorders

Led by Cairo University · Updated on 2024-08-16

33

Participants Needed

1

Research Sites

24 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study aims to compere mandibular splint versus botox injection in lateral pterygoid on cervical muscle activity in patients with temporomandibular disorders

CONDITIONS

Official Title

Mandibular Splint vs Botox Injection in Lateral Pterygoid on Cervical Muscle Activity in Patients With Temporomandibular Disorders

Who Can Participate

Age: 18Years - 40Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age from 18-40 years old.
  • Both sexes.
  • Duration of the disease is more than 3 months.
  • Anterior mandibular disc displacement with reduction.
  • Unilateral anterior mandibular displacement with reduction grade 2 and 3 (Wilkes).
  • Patients with cervical muscle spasm and trigger points (upper trapezius and sternocleidomastoid).
  • Patients with sufficient cognitive abilities to understand and follow instructions.
Not Eligible

You will not qualify if you...

  • Neurological or musculoskeletal diseases affecting cervical spine other than mandibular disc displacement (e.g., cervical spondylosis, spondylolisthesis, cervical disc injuries).
  • Bilateral anterior mandibular disc displacement.
  • Severe musculoskeletal disorders such as arthritis, cervical spine surgery, contractures, or leg length discrepancy.
  • Women who are pregnant or breastfeeding.
  • Known hypersensitivity to any drug components, especially human albumin.
  • Infection or inflammation at planned injection sites.
  • Musculoskeletal conduction disorders and primary muscular disorders (e.g., muscular dystrophy, neuromyopathy).
  • Current treatment with certain antibiotics or drugs (aminoglycosides, ciclosporin, D-penicillamine, etc.).
  • History of cervical spine surgery or trauma.
  • Signs of cervical radiculopathy, myelopathy, or vascular syndromes.
  • Signs of serious pathology such as malignancy, inflammatory disorders, or infection.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cairo University

Cairo, Egypt, 11796

Actively Recruiting

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Research Team

K

Kerolos G Abd-El Malak, MBBCH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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