Comparing Mandibular Splint and Botox Injection in the Lateral Pterygoid Muscle for Cervical Muscle Activity in Adults with Temporomandibular Disorders

What this Trial Is About

This research aims to compare the effects of mandibular splint and Botox injection in the lateral pterygoid muscle on cervical muscle activity in patients with temporomandibular disorders TMD. TMD involves pain and dysfunction in the jaw joint and muscles controlling jaw movement, often caused by internal displacement of the joints disc. The study addresses common chronic musculoskeletal pain conditions affecting the orofacial area, focusing on how different treatments may influence muscle activity in this population. Participants are randomly assigned to one of three groups Botox injection in the lateral pterygoid muscle combined with medications muscle relaxants, antidepressants, and nonsteroidal anti-inflammatory drugs mandibular stabilization splint combined with the same medications or medication treatment alone. Botox is prepared at a concentration of 10 units per 0.1 mL and injected into the affected muscle, while the splint is worn as a dental device to realign the jaw. The study period includes treatment and follow-up to assess outcomes over three months. During the study, researchers measure muscle activity in the upper trapezius and sternocleidomastoid muscles three months after treatment. They evaluate amplitude and root mean square of muscle activity to assess treatment effects. Participants undergo regular monitoring, including assessments of symptoms and muscle function, with attention to safety and adherence. The total study duration extends from enrollment until three months post-treatment, with ongoing observation of cervical muscle activity changes.

Mandibular Splint vs Botox Injection in Lateral Pterygoid on Cervical Muscle Activity in Patients With Temporomandibular Disorders