Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06148077

Manual Therapy on Oral Opening, Swallow Function and Upper Quarter Mobility on Head and Neck Cancer Survivors

Led by Universidad de La Frontera · Updated on 2025-05-30

70

Participants Needed

2

Research Sites

53 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Trismus has been reported as the second most common comorbidity in survivors of head and neck cancer (HNC). It is mainly associated with post-radiotherapy subcutaneous fibrosis, muscular atrophy, damage to neurological structures in the neck, or a combination of all, affecting masticatory musculature. In addition to this, the loss of flexibility and strength in the shoulder has also been shown to be related to deficits in the function and quality of life of these patients. The goal of this clinical trial is to determinate the effectiveness and safety of Manual Therapy (MT) on Oral Opening, Swallow Function, as well as the mobility of the upper quarter, the strength of cervical musculature, pain, functionality, and the perception of quality of life in head and neck cancer survivors. Participants will be assigned randomly to the study groups: a) manual therapy program and control motor exercises and b) motor control exercises (usual care). The assessment refers to a baseline form (at the beginning of the study), at 6 weeks and at 6 weeks of patient follow-up.

CONDITIONS

Official Title

Manual Therapy on Oral Opening, Swallow Function and Upper Quarter Mobility on Head and Neck Cancer Survivors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals diagnosed with head and neck cancer
  • Age 18 years or older
  • Individuals who have had oncological surgery and/or radiotherapy on the head and neck
  • Completed cancer treatment between 3 and 36 months prior to joining
  • Medical diagnosis of trismus, temporomandibular disorders, or cervical or shoulder dysfunction
  • Native Spanish speakers
Not Eligible

You will not qualify if you...

  • History of previous stroke
  • Structural instability or osteoporosis of the cervical spine, spondylosis, or cervical herniated discs
  • Active osteoradionecrosis or open wounds such as fistulas or soft tissue necrosis in the treatment area
  • Individuals with a tracheostomy
  • Presence of metastasis or active cancer
  • Those who refuse to participate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Barbara Burgos Mansilla

Temuco, Cautin, Chile

Actively Recruiting

2

Universidad de La Frontera

Temuco, Cautin, Chile

Actively Recruiting

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Research Team

B

Barbara Burgos, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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