Actively Recruiting

Age: 18Years - 90Years
All Genders
Healthy Volunteers
NCT06588452

Manual Versus AI-Assisted Clinical Trial Screening Using Large-Language Models

Led by Brigham and Women's Hospital · Updated on 2024-09-19

4500

Participants Needed

1

Research Sites

27 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A prospective randomized controlled trial comparing manual review and AI screening for patient eligibility determination and enrollments. A structured query will identify potentially eligible patients from the Mass General Brigham Electronic Data Warehouse (EDW), who will then be randomized into either the manual review arm or the AI-assisted review arm.

CONDITIONS

Official Title

Manual Versus AI-Assisted Clinical Trial Screening Using Large-Language Models

Who Can Participate

Age: 18Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Documented diagnosis of heart failure (e.g., ICD-9 codes 428 ICD-10 codes I50 or Problem list in the electronic health record)
  • Most recent left ventricular ejection fraction (LVEF) assessed within the past 24 months
  • Seen Mass General Brigham provider within the last 24 months
Not Eligible

You will not qualify if you...

  • LVEF <50% currently prescribed or intolerant to an evidence-based beta-blocker, ARNI, MRA, and SGLT2i at least 50% goal dose
  • LVEF >50% currently prescribed or intolerant to SGLT2i
  • Systolic blood pressure (SBP) <90 mmHg at last measure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Brigham and Women's Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

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Research Team

O

Ozan Unlu, MD

CONTACT

A

Alexander J Blood, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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