Actively Recruiting

Age: 18Years +
FEMALE
Healthy Volunteers
NCT05253352

Mapping and Quantifying Lymphatic Drainage of the Arm's Alternate Pathway

Led by Beth Israel Deaconess Medical Center · Updated on 2026-03-11

142

Participants Needed

1

Research Sites

243 weeks

Total Duration

On this page

Sponsors

B

Beth Israel Deaconess Medical Center

Lead Sponsor

N

National Heart, Lung, and Blood Institute (NHLBI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Using indocyanine green (ICG) lymphography and lymphoscintigraphy with SPECT/CT imaging, the aim is to evaluate the anatomy of the lymphatic system pathway in two separate populations: healthy female volunteers and women with a history of breast cancer who did not develop lymphedema.

CONDITIONS

Official Title

Mapping and Quantifying Lymphatic Drainage of the Arm's Alternate Pathway

Who Can Participate

Age: 18Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Female
  • History of breast cancer treatment including ALND defined by removal of 10 or more lymph nodes more than 2 years before study participation
  • Ability to understand the protocol and willingness to participate
  • At least 18 years of age
Not Eligible

You will not qualify if you...

  • Prior history of bilateral lymph node surgery
  • Prior history of other surgical procedures of the affected upper extremity besides the axillary management for breast cancer treatment
  • Prior history of chronic inflammatory conditions such as rheumatoid arthritis
  • Prior history of filarial infections
  • Prior history of lymphedema
  • Patient-reported pregnancy
  • Patients who are breastfeeding
  • Iodine allergy
  • Prior history of upper extremity deep vein thrombosis
  • Prior history of congestive heart failure
  • Prior history of venous thoracic outlet syndrome
  • Current active cancer

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States, 02215

Actively Recruiting

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Research Team

A

Angela Chen, BS

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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