Actively Recruiting
MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)
Led by University of Southern California · Updated on 2026-05-13
600
Participants Needed
9
Research Sites
209 weeks
Total Duration
On this page
Sponsors
U
University of Southern California
Lead Sponsor
P
Patient-Centered Outcomes Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study is an intervention domain of the Musculoskeletal Adaptive Platform Trial. The primary goal of this pragmatic, randomized, open-label, comparative effectiveness trial is to evaluate if arthroplasty is superior to internal fixation when used to treat minimally displaced femoral neck fractures in older adults ≥60 years old. We hypothesize that arthroplasty will reduce death, preserve ambulation, increase days alive and out of hospital, and improve health status compared to internal fixation within 4 months and 12 months from randomization.
CONDITIONS
Official Title
MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 60 years of age or older undergoing surgery due to a minimally displaced femoral neck fracture
- Health condition affecting physical mobility
- Complete femoral neck fracture confirmed by hip X-rays, CT, or MRI
- Fracture judged by surgeon to be treatable with either arthroplasty or internal fixation without reduction
- Injury caused by low-energy mechanism
- Availability of surgeons skilled in internal fixation and hip arthroplasty
You will not qualify if you...
- Patient not suitable for either treatment option
- Expected survival less than 12 months
- Terminal illness with survival under 12 months
- Incarceration
- Unable to provide informed consent due to language or lack of authorized representative
- Problems maintaining follow-up
- Enrollment in conflicting studies or prior enrollment in this trial domain
- Declined participation or missed screening window
- Other exclusions approved by data coordinating center
- Associated lower limb injury preventing post-operative weight-bearing
- Retained hardware around hip blocking study treatments
- Infection around the hip
- Pathologic fracture with a lytic lesion preventing internal fixation
- Injury occurred more than 21 days before screening
- Patient too ill for internal fixation or arthroplasty according to surgeon
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 9 locations
1
University of California, Irvine
Irvine, California, United States, 92660
Actively Recruiting
2
Los Angeles General Medical Center
Los Angeles, California, United States, 90033
Actively Recruiting
3
University of Southern California
Los Angeles, California, United States, 90033
Actively Recruiting
4
Indiana University
Bloomington, Indiana, United States, 47405
Actively Recruiting
5
University of Maryland, Baltimore - R Adams Cowley Shock Trauma Center
Baltimore, Maryland, United States, 21201
Actively Recruiting
6
University of Maryland Capital Region Health
Largo, Maryland, United States, 20774
Actively Recruiting
7
University of Mississippi
University, Mississippi, United States, 38677
Actively Recruiting
8
University of British Columbia
Vancouver, British Columbia, Canada, V6T 1Z4
Actively Recruiting
9
Fraser Health Authority
Vancouver, British Columbia, Canada
Actively Recruiting
Research Team
J
Joseph Patterson, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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