Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04086082

Markerless Image Guidance Using Intrafraction Kilovoltage X-ray Imaging

Led by University of Sydney · Updated on 2024-01-11

30

Participants Needed

1

Research Sites

288 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This trial will investigate the feasibility of the Markerless Tumour Tracking technology.

CONDITIONS

Official Title

Markerless Image Guidance Using Intrafraction Kilovoltage X-ray Imaging

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Willing to follow all trial procedures and provide written informed consent
  • Undergoing external beam radiotherapy
  • Histologically confirmed Stage I non-small cell lung cancer or up to three lung metastases
  • MRI or 4D-CT performed before fiducial marker insertion
  • Able to have fiducial markers placed in the lung (with clearance if on anticoagulants)
  • ECOG performance status between 0 and 2
  • Maximum of three lung metastases from non-blood cancers, treated separately
  • Tumor diameter between 1 cm and 5 cm in any dimension
  • Tumor centroid located within 10 cm of the top of the diaphragm
Not Eligible

You will not qualify if you...

  • Low respiratory performance as assessed by a doctor
  • Previous high-dose radiation therapy to the chest
  • Fewer than one fiducial marker implanted in the lung
  • Fiducial markers located more than 9 cm from the tumor centroid
  • Cytotoxic chemotherapy within 3 weeks before or during treatment
  • Targeted therapy drugs within 7 days before or during treatment
  • Women who are pregnant or breastfeeding
  • Unable or unwilling to complete quality of life questionnaires

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Alfred Health

Melbourne, Victoria, Australia, 3004

Actively Recruiting

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Research Team

T

Trial Coordinator

CONTACT

R

Research Student

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Markerless Image Guidance Using Intrafraction Kilovoltage X-ray Imaging | DecenTrialz