Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT06948435

A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1

Led by Eli Lilly and Company · Updated on 2026-04-17

487

Participants Needed

99

Research Sites

122 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

GZL1 is an independent study conducted under the GZPL master protocol. GZL1 will evaluate the efficacy and safety of orforglipron for treatment of hypertension in participants with obesity or overweight.

CONDITIONS

Official Title

A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Refer to the GZPL master protocol for screening eligibility.
Not Eligible

You will not qualify if you...

  • Refer to the GZPL master protocol for screening eligibility.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 99 locations

1

Elite Clinical Studies, LLC

Phoenix, Arizona, United States, 85018

Active, Not Recruiting

2

Valley Clinical Trials, Inc.

Covina, California, United States, 91723

Active, Not Recruiting

3

Valley Clinical Trials, Inc.

Northridge, California, United States, 91325

Active, Not Recruiting

4

Chase Medical Research, LLC

Waterbury, Connecticut, United States, 06708

Active, Not Recruiting

5

Excel Medical Clinical Trials

Boca Raton, Florida, United States, 33434

Active, Not Recruiting

6

Care Access - Brandon

Brandon, Florida, United States, 33510

Active, Not Recruiting

7

Northeast Research Institute - Downtown Office

Jacksonville, Florida, United States, 32204

Active, Not Recruiting

8

Peace River Cardiovascular Center

Port Charlotte, Florida, United States, 33952

Not Yet Recruiting

9

East-West Medical Research Institute

Honolulu, Hawaii, United States, 96814

Active, Not Recruiting

10

Ascension Saint Agnes Heart Care

Baltimore, Maryland, United States, 21229

Active, Not Recruiting

11

Lucida Clinical Trials

New Bedford, Massachusetts, United States, 02740

Active, Not Recruiting

12

Arcturus Healthcare , PLC, Troy Internal Medicine Research Division

Troy, Michigan, United States, 48098

Active, Not Recruiting

13

StudyMetrix Research

City of Saint Peters, Missouri, United States, 63303

Active, Not Recruiting

14

Excel Clinical Research, LLC

Las Vegas, Nevada, United States, 89109

Active, Not Recruiting

15

Palm Research Center Sunset

Las Vegas, Nevada, United States, 89148

Active, Not Recruiting

16

Rochester Clinical Research, LLC

Rochester, New York, United States, 14609

Active, Not Recruiting

17

Remington-Davis, Inc

Columbus, Ohio, United States, 43215

Active, Not Recruiting

18

PriMED Clinical Research

Dayton, Ohio, United States, 45429

Active, Not Recruiting

19

Advanced Research Institute - Tigard

Tigard, Oregon, United States, 97223

Active, Not Recruiting

20

Care Access - Mauldin

Mauldin, South Carolina, United States, 29662

Active, Not Recruiting

21

Dallas Heart and Vascular Consultants, PA

Duncanville, Texas, United States, 75137

Active, Not Recruiting

22

Texas Institute of Cardiology, PA

McKinney, Texas, United States, 75071

Active, Not Recruiting

23

North Hills Family Medicine/North Hills Medical Research

North Richland Hills, Texas, United States, 76180

Active, Not Recruiting

24

Advanced Research Institute

Ogden, Utah, United States, 84405

Active, Not Recruiting

25

Carient Heart & Vascular - Manassas

Manassas, Virginia, United States, 20109

Active, Not Recruiting

26

Health Research of Hampton Roads, Inc.

Newport News, Virginia, United States, 23606

Active, Not Recruiting

27

National Clinical Research, Inc

Richmond, Virginia, United States, 23294

Active, Not Recruiting

28

Eastside Research Associates

Redmond, Washington, United States, 98052

Active, Not Recruiting

29

Instituto Médico Especializado (IME)

Buenos Aires, Argentina, 1405

Active, Not Recruiting

30

CIPREC

Buenos Aires, Argentina, C1061AAS

Active, Not Recruiting

31

CIPREC

Buenos Aires, Argentina, C1119ACN

Active, Not Recruiting

32

CEMEDIC

Buenos Aires, Argentina, C1407GTN

Active, Not Recruiting

33

Instituto de Investigaciones Clínicas Córdoba

Córdoba, Argentina, 5000

Active, Not Recruiting

34

Centro de Investigaciones Clínicas Baigorria

Granadero Baigorria, Argentina, 2152

Active, Not Recruiting

35

INECO Neurociencias Oroño

Rosario, Argentina, 2000

Active, Not Recruiting

36

Instituto Médico Fundación Grupo Colaborativo Rosario Investigación y Prevención Medica

Rosario, Argentina, 2000

Active, Not Recruiting

37

Santa Maria de la Salud Centro Medico

San Isidro, Argentina, 1642

Active, Not Recruiting

38

Beijing Pinggu District Hospital

Beijing, China, 101200

Active, Not Recruiting

39

China-Japan Union Hospital

Changchun, China, 130033

Active, Not Recruiting

40

Changde First People's Hospital

Changde, China, 415000

Active, Not Recruiting

41

Sichuan Provincial People's Hospital

Chengdu, China, 610072

Active, Not Recruiting

42

The Second Affiliated Hospital of Chongqing Medical University - Yuzhong Campus

Chongqing, China, 400010

Active, Not Recruiting

43

Jinan Central Hospital

Jinan, China, 250013

Active, Not Recruiting

44

Lishui Central Hospital

Lishui, China

Active, Not Recruiting

45

The First Affiliated Hospital of Henan University of Science &Technology

Luoyang Shi, China, 471003

Active, Not Recruiting

46

Ruijin Hospital Shanghai Jiaotong University School of Medicine

Shanghai, China, 200001

Active, Not Recruiting

47

Siping Central People's Hospital

Siping, China, 136000

Active, Not Recruiting

48

Wuxi People's Hospital

Wuxi, China, 214023

Active, Not Recruiting

49

Shaanxi provincial people's hospital

Xi'an, China, 710068

Active, Not Recruiting

50

Top Moravia Health

Brno, Czechia, 61500

Active, Not Recruiting

51

Ordinace Rihackovi, s.r.o.

Brno, Czechia, 641 00

Active, Not Recruiting

52

CTC Hodonin s.r.o.

Hodonín, Czechia, 695 01

Active, Not Recruiting

53

MUDr. Sarka Drinkova

Ledeč nad Sázavou, Czechia, 584 01

Active, Not Recruiting

54

CCR Ostrava s.r.o

Ostrava, Czechia, 702 00

Active, Not Recruiting

55

Diahelp s.r.o

Pardubice V, Czechia, 530 02

Active, Not Recruiting

56

Clinoxus

Prague, Czechia, 140 00

Active, Not Recruiting

57

Angiocentrum Komorany

Prague, Czechia, 143 00

Active, Not Recruiting

58

Praglandia s.r.o

Prague, Czechia, 150 00

Active, Not Recruiting

59

Zentrum für klinische Studien Bad Homburg

Bad Homburg, Germany, 61348

Active, Not Recruiting

60

FutureMeds GmbH

Berlin, Germany, 10629

Active, Not Recruiting

61

Zentrum fur klinische Forschung - Köln

Cologne, Germany, 51069

Active, Not Recruiting

62

Hausärztlich-Kardiologisches MVZ am Felsenkeller GmbH/Zentrum für klinische Studien

Dresden, Germany, 01277

Active, Not Recruiting

63

Universitaetsklinikum Carl Gustav Carus Dresden

Dresden, Germany, 01307

Active, Not Recruiting

64

Medizentrum Essen Borbeck

Essen, Germany, 45355

Active, Not Recruiting

65

AmBeNet GmbH

Leipzig, Germany, 04107

Active, Not Recruiting

66

Familienmedizinisches Zentrum Radowsky

Leipzig, Germany, 04179

Active, Not Recruiting

67

RED-Institut GmbH

Oldenburg, Germany, 23758

Active, Not Recruiting

68

Athens Medical Center - Psychikon branch

Athens, Greece, 115 25

Active, Not Recruiting

69

General Hospital of Athens "G. Gennimatas"

Athens, Greece, 11527

Active, Not Recruiting

70

University Hospital of Ioannina

Ioannina, Greece, 45500

Active, Not Recruiting

71

G. Gennimatas General Hospital of Thessaloniki

Thessaloniki, Greece, 546 35

Active, Not Recruiting

72

AHEPA University General Hospital of Thessaloniki

Thessaloniki, Greece, 546 36

Active, Not Recruiting

73

Papageorgiou General Hospital of Thessaloniki

Thessaloniki, Greece, 56403

Active, Not Recruiting

74

Life Care Hospital and Research Centre

Bangalore, India, 560092

Actively Recruiting

75

All India Institute of Medical Sciences

Bhubaneswar, India, 751019

Actively Recruiting

76

G.B. Pant Institute of Postgraduate Medical Education & Research

New Delhi, India, 110002

Actively Recruiting

77

Ashirwad Hospital and Research Centre

Ulhasnagar, India, 421004

Actively Recruiting

78

Tokyo-Eki Center-building Clinic

Chūōku, Japan, 103-0027

Active, Not Recruiting

79

Fukuwa Clinic

Chūōku, Japan, 104-0031

Active, Not Recruiting

80

Takai Internal Medicine Clinic

Kamakura-shi, Japan, 247-0056

Active, Not Recruiting

81

Mikannohana Clinic, Diabetes, Endocrinology and Metabolism

Matsuyama, Japan, 7900034

Active, Not Recruiting

82

Medical Corporation Yuga Tsuruma Kaneshiro Diabetes Clinic

Yamato-shi, Japan, 242-0004

Active, Not Recruiting

83

Uniwersytecki Szpital Kliniczny w Białymstoku

Bialystok, Poland, 15-276

Active, Not Recruiting

84

Centrum Medyczne "Hipokrates" S.C. Elżbieta I Grzegorz Grześk

Bydgoszcz, Poland, 85-092

Active, Not Recruiting

85

NZOZ Centrum Medyczne KERmed

Bydgoszcz, Poland, 85-231

Active, Not Recruiting

86

IRMED

Piotrkow Trybunalski, Poland, 97-300

Active, Not Recruiting

87

Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu

Przemyśl, Poland, 37-700

Active, Not Recruiting

88

Private Practice - Dr. Robert Witek

Tarnów, Poland, 33-100

Active, Not Recruiting

89

Balsam Medica

Warsaw, Poland, 01-249

Active, Not Recruiting

90

NZOZ Regionalna Poradnia Diabetologiczna

Wroclaw, Poland, 50-127

Active, Not Recruiting

91

Dorado Medical Complex

Dorado, Puerto Rico, 00646

Active, Not Recruiting

92

Puerto Rico Medical Research

Ponce, Puerto Rico, 00717

Active, Not Recruiting

93

CHUAC-Complejo Hospitalario Universitario A Coruña

A Coruña, Spain, 15001

Active, Not Recruiting

94

Hospital San Rafael - La Coruña

A Coruña, Spain, 15006

Active, Not Recruiting

95

EAP Sardenya

Barcelona, Spain, 08025

Active, Not Recruiting

96

EAP Osona Sud - Alt Congost S.L.P

Centelles, Spain, 08540

Active, Not Recruiting

97

Complejo Asistencial Universitario de León - Hospital de León

León, Spain, 24071

Active, Not Recruiting

98

Clínica nuevas Tecnologías en Diabetes y Endocrinología (NTDE)

Seville, Spain, 41003

Active, Not Recruiting

99

Hospital Quiron Infanta Luisa

Seville, Spain, 41010

Active, Not Recruiting

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Research Team

T

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or

CONTACT

P

Physicians interested in becoming principal investigators please contact

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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