Actively Recruiting
Matching Treatments to Cognitive Deficits in Offenders With Substance Use Disorders
Led by The Mind Research Network · Updated on 2025-05-20
288
Participants Needed
1
Research Sites
219 weeks
Total Duration
On this page
Sponsors
T
The Mind Research Network
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to investigate the effect of two types of cognitive remediation training on real-world behavioral outcomes including substance use, institutional adjustment, and recidivism following release from prison. Each training type is designed to target one of two subtypes of antisocial criminal offenders, who are characterized by either: 1) Attention to context-based deficits, or 2) Affective cognitive control-based deficits. The main questions it aims to answer are: Does matching deficit type with targeted cognitive training improve outcomes (relative to mismatched training)? What are the functional brain mechanisms that underlie treatment change? Participants will: Be assigned to cognitive training that either does or does not match their deficit type. Complete six one-hour sessions of cognitive skills training. Complete pre and post-training behavioral tasks assessing self-regulation deficits. Complete structural MRI scans and functional MRI scans assessing cognitive control. Complete post-treatment follow-up assessments evaluating self-regulation, adjustment, and stressful life events, substance use and recidivism.
CONDITIONS
Official Title
Matching Treatments to Cognitive Deficits in Offenders With Substance Use Disorders
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Currently incarcerated
- No uncorrectable auditory or visual deficits
- Able to speak and/or understand English
- 5th grade reading level or higher
- IQ score = 80 or above
- Lifetime history of substance use disorder based on DSM criteria
- No history of dementia or other cognitive disability
- No indication of current psychotic disorder
- No major medical illness or CNS disease
- Scores from the Psychopathy Checklist-Revised (PCL-R) meet criteria for one of the designated treatment groups
You will not qualify if you...
- None
AI-Screening
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Trial Site Locations
Total: 1 location
1
Mind Research Network/Lovelace Biomedical Research Institute
Albuquerque, New Mexico, United States, 87106
Actively Recruiting
Research Team
C
Carla Harenski
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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