Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
FEMALE
NCT06919692

Maternal Left Lateral Position in Fetal Growth Restriction

Led by University of Colorado, Denver · Updated on 2025-07-17

100

Participants Needed

2

Research Sites

70 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if maternal left-lateral positioning in pregnancy works to treat fetal growth restriction. This study will also help us learn about the effects of left-lateral positioning on maternal metabolomics, maternal mental health, fetal cardiac function, and delivery outcomes. The main questions it aims to answer are: * Does maternal left-lateral position in a pregnancy with fetal growth restriction improve the baby's growth? * How are maternal metabolomics, delivery outcomes, maternal mental health, and fetal cardiac function impacted by maternal left-lateral position? Researchers will compare the intervention group to pregnancies with fetal growth restriction that receive standard of care (without left-lateral positioning) to see if left-lateral position improves fetal biometry in fetal growth restriction. Participants will: * Practice left-lateral position every day for 4 hours (cumulatively) with 10-mins stretching after every hour of left-lateral position, or continue to receive standard of care * Visit the clinic once after 4 weeks for a follow-up research visit, and at the time of delivery Tracking of the physical activity and adherence to left-lateral position at home in intervention group A will be done through a fitbit (smart watch) given during enrollment. A fitbit will also be given to participants in intervention group B, receiving standard of care, to monitor their physical activity trends at home.

CONDITIONS

Official Title

Maternal Left Lateral Position in Fetal Growth Restriction

Who Can Participate

Age: 18Years - 65Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant persons between 18 and 65 years old with fetal growth restriction and estimated fetal weight below the tenth percentile
  • Singleton pregnancy between 24 and 34 weeks gestational age
  • Fluency in English or Spanish language
Not Eligible

You will not qualify if you...

  • History of deep vein thrombosis, pulmonary embolism, or hypercoagulability disorder
  • Pre-pregnancy body mass index greater than 40
  • Severe abnormality in umbilical artery Doppler flow, including absent or reverse end-diastolic flow
  • Receiving anticoagulation therapy
  • Pregnancy with suspected chromosomal anomalies or multifetal pregnancy
  • Active smoking during pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 2 locations

1

UCHealth Prenatal Diagnosis and Genetics Clinic - Anschutz Medical Campus

Aurora, Colorado, United States, 80045

Actively Recruiting

2

CU John C. Hobbins Perinatal Center

Denver, Colorado, United States, 80202

Actively Recruiting

Loading map...

Research Team

H

Hannah E Vincent, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here