Actively Recruiting
Maternal Left Lateral Position in Fetal Growth Restriction
Led by University of Colorado, Denver · Updated on 2025-07-17
100
Participants Needed
2
Research Sites
70 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if maternal left-lateral positioning in pregnancy works to treat fetal growth restriction. This study will also help us learn about the effects of left-lateral positioning on maternal metabolomics, maternal mental health, fetal cardiac function, and delivery outcomes. The main questions it aims to answer are: * Does maternal left-lateral position in a pregnancy with fetal growth restriction improve the baby's growth? * How are maternal metabolomics, delivery outcomes, maternal mental health, and fetal cardiac function impacted by maternal left-lateral position? Researchers will compare the intervention group to pregnancies with fetal growth restriction that receive standard of care (without left-lateral positioning) to see if left-lateral position improves fetal biometry in fetal growth restriction. Participants will: * Practice left-lateral position every day for 4 hours (cumulatively) with 10-mins stretching after every hour of left-lateral position, or continue to receive standard of care * Visit the clinic once after 4 weeks for a follow-up research visit, and at the time of delivery Tracking of the physical activity and adherence to left-lateral position at home in intervention group A will be done through a fitbit (smart watch) given during enrollment. A fitbit will also be given to participants in intervention group B, receiving standard of care, to monitor their physical activity trends at home.
CONDITIONS
Official Title
Maternal Left Lateral Position in Fetal Growth Restriction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pregnant persons between 18 and 65 years old with fetal growth restriction and estimated fetal weight below the tenth percentile
- Singleton pregnancy between 24 and 34 weeks gestational age
- Fluency in English or Spanish language
You will not qualify if you...
- History of deep vein thrombosis, pulmonary embolism, or hypercoagulability disorder
- Pre-pregnancy body mass index greater than 40
- Severe abnormality in umbilical artery Doppler flow, including absent or reverse end-diastolic flow
- Receiving anticoagulation therapy
- Pregnancy with suspected chromosomal anomalies or multifetal pregnancy
- Active smoking during pregnancy
AI-Screening
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Trial Site Locations
Total: 2 locations
1
UCHealth Prenatal Diagnosis and Genetics Clinic - Anschutz Medical Campus
Aurora, Colorado, United States, 80045
Actively Recruiting
2
CU John C. Hobbins Perinatal Center
Denver, Colorado, United States, 80202
Actively Recruiting
Research Team
H
Hannah E Vincent, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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