Prevention of Perinatal Depression in At-Risk Pregnant and Postpartum Women Using a Digital Mindfulness-Based Cognitive Therapy Program Integrated in Healthcare

What this Trial Is About

Researchers are evaluating a digital mental health program designed to prevent perinatal depression in diverse groups of at-risk pregnant and postpartum women. This project focuses on understanding how well the program can be integrated into healthcare settings serving rural, urban, and Latino populations. The study uses a randomized preference design to explore how patient and sociocultural factors affect engagement and symptom changes over time. The interventions include a manualized Mindfulness-Based Cognitive Behavioral Therapy program called UPLIFT, adapted for remote access through a patient portal. Participants may receive on-demand multimedia content alone or combined with either a discussion board or videoconference support sessions. The videoconference sessions are shorter than usual, with four one-hour meetings every two weeks. These options are tested to refine the approach and prepare for larger future trials. Participants will be involved for up to 18 months, during which researchers will assess how feasible and acceptable the program is in clinical settings. Evaluations occur at 6, 12, and 18 months and include measuring sociocultural influences and behavior changes. The study collects input from patients and community stakeholders regularly to improve the implementation process and ensure it fits diverse populations and care environments.

Maternal Mental Health Access - MaMa