Actively Recruiting
Maxillomandibular Advancement Surgery for Treatment of Obstructive Sleep Apnoea Syndrome
Led by Jani Talvilahti · Updated on 2026-03-03
48
Participants Needed
1
Research Sites
959 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study looks at how jaw surgery called maxillomandibular advancement with counterclockwise rotation affects breathing during sleep in people with moderate to severe obstructive sleep apnea who cannot tolerate standard treatments such as Continous Positive Airway pressure treatment. The participants are followed over time to see whether the surgery improves sleep apnea symptoms, daytime sleepiness, and airway size, and whether these improvements last. Advanced three-dimensional imaging and airflow analysis are used to better understand how the surgery changes the airway and breathing. The goal is to evaluate the long-term effectiveness and safety of this surgical treatment.
CONDITIONS
Official Title
Maxillomandibular Advancement Surgery for Treatment of Obstructive Sleep Apnoea Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of obstructive sleep apnea with AHI 615 events/h
- Residence and/or registration in Dalarna County
- Body mass index (BMI) between 15 and 35 kg/m
- Documented failure of CPAP or mandibular advancement therapy
You will not qualify if you...
- Medical conditions contraindicating general anesthesia
- American Society of Anesthesiologists Physical Status (ASA) Class III-VI
- Central sleep apnea
- Narcolepsy
- Prior orthognathic surgery
- History of tumor disease or radiotherapy of the jaws
- Systemic conditions increasing risk of OSA including hypothyroidism, acromegaly, diabetes mellitus, active generalized rheumatoid arthritis
- Clinically manifest periodic limb movement disorder
- Restless legs syndrome
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Falu Hospital
Falun, Dalarna County, Sweden, 79182
Actively Recruiting
Research Team
J
Jani M A Talvilahti, DDS, Head
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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