Actively Recruiting
Maximizing the Benefits of Iron in Ready-to-Use Therapeutic Foods for Malnourished Children in Kenya
Led by ETH Zurich · Updated on 2026-01-02
68
Participants Needed
2
Research Sites
27 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Reports from the Kenya Red Cross Society (KRCS) in Kwale County, southern Kenya, indicate a limited impact of Ready-to-Use Therapeutic Foods (RUTFs) on malnutrition or anemia. The current RUTF formulation may have an excessively high iron content. In severely acutely malnourished (SAM) children, iron cannot be properly absorbed, leading to life-threatening diarrhea. The overall aim of this project is to develop an improved RUTF treatment that addresses acute malnutrition and anemia in children, ensuring both safety and efficacy. Specifically, to assess the impact of malnutrition on fractional iron absorption (FIA) from RUTFs in children, by comparing healthy children to those with acute malnutrition and by tracking changes in FIA in malnourished children over the course of treatment.
CONDITIONS
Official Title
Maximizing the Benefits of Iron in Ready-to-Use Therapeutic Foods for Malnourished Children in Kenya
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children aged between 1 and 4.5 years
- Children with severe acute malnutrition (weight-for-height Z-score less than -3.0)
- Children with moderate acute malnutrition (weight-for-height Z-score less than -2.0)
- Children treated as outpatients with no acute medical conditions and a positive appetite test
- Healthy children with height-for-age, weight-for-age, and weight-for-height Z-scores equal to 0
You will not qualify if you...
- Hemoglobin level less than 7 g/dL
- Presence of acute medical conditions requiring inpatient treatment
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
ETH/Oxford/JKUAT research facility
Msambweni, Kwale County, Kenya
Actively Recruiting
2
ETH Zurich, Laboratory of Clinical Biopharmacy, Zurich, 8092
Zurich, Switzerland, 8006
Not Yet Recruiting
Research Team
S
Suzane Nyilima, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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