Actively Recruiting
MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
Led by University of California, San Francisco · Updated on 2025-09-11
516
Participants Needed
5
Research Sites
52 weeks
Total Duration
On this page
Sponsors
U
University of California, San Francisco
Lead Sponsor
P
Patient-Centered Outcomes Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of two different ways to provide cardiac rehabilitation to patients with heart conditions such as myocardial infarction, heart failure, and coronary artery disease. The study aims to compare traditional in-person cardiac rehabilitation to a telehealth program to see if both methods have similar benefits and to identify which patients might benefit more from each approach. Participants will be randomly assigned to one of two groups. One group will take part in a 12-week in-person cardiac rehabilitation program consisting of 36 group sessions including exercise, health education, and counseling. The other group will participate in a 12-week telehealth cardiac rehabilitation program with the same core components but delivered through weekly individual telehealth sessions without supervised in-person exercise. During the study, participants will be assessed at the start and followed up at 3, 12, and 24 months. Researchers will measure changes in physical abilities using a six-minute walk test, mental and physical health through questionnaires, anxiety and depression scores, blood pressure control, participation rates, and survival free of hospitalization for heart-related events. The total participation lasts up to 24 months with ongoing monitoring of health outcomes.
CONDITIONS
Brief Title
MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 or older
- Eligible for cardiac rehabilitation with diagnosis within 1 year prior to consent including myocardial infarction, percutaneous coronary intervention, coronary artery bypass, heart valve repair or replacement, or heart transplant
- Chronic stable angina or chronic systolic heart failure with ejection fraction 64 35%
- Referred to cardiac rehabilitation by a doctor or advanced practice provider for indications covered by insurance
- Willing to be randomized to in-person or telehealth cardiac rehabilitation
- Able to communicate in English or Spanish
You will not qualify if you...
- Unstable arrhythmias making unmonitored exercise unsafe
- Considered unsafe to participate by the investigator
- Receiving hospice care
- Unable to consent for self
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 12 weeks
Participants undergo 12 weeks of cardiac rehabilitation either in-person with group exercise, health education, and counseling, or via telehealth with weekly individual telehealth sessions.
36 sessions for in-person cardiac rehabilitation or 12 weekly telehealth sessions for telehealth cardiac rehabilitation
Duration - Up to 24 months
Participants are followed for up to 24 months to assess health outcomes including physical and mental health, blood pressure control, and survival free of hospitalization.
Visits at 3 months, 12 months, and 24 months
Trial Site Locations
Total: 5 locations
1
University of California, San Francisco
San Francisco, California, United States, 94143
Actively Recruiting
2
Denver Health
Denver, Colorado, United States, 80204
Actively Recruiting
3
Johns Hopkins University Medical Center
Baltimore, Maryland, United States, 21287
Actively Recruiting
4
University of Michigan
Ann Arbor, Michigan, United States, 48105
Actively Recruiting
5
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States, 15232
Actively Recruiting
Research Team
A
Alisa Boyd, MPH
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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