Measurement Properties of Physical Function Assessments in Adults with Hemophilia Evaluating Reliability and Validity of Clinical Tests

What this Trial Is About

This research aims to validate the accuracy and reliability of clinical tests that measure different aspects of physical function in adults with hemophilia. Hemophilia treatment has improved, but affected individuals still face challenges like limited mobility, reduced strength, poor balance, and pain caused by repeated bleeding. The study addresses the need to confirm that these clinical assessments are suitable and effective for adults with hemophilia, as previous research mainly involved children or other conditions. The study evaluates six physical function tests: Short Physical Performance Battery, Unipedal Stance Test, Four Square Step Test, Timed Up and Go, 1 kg Arm Lift Test, and 30 Second Chair Stand Test. These assessments are already used in practice and are considered safe with minimal strain. The study will assess the reliability of these tests by repeating them after a minimum 48-hour break and will check their validity by comparing results with other health measures, such as the Short Form 36 and Hemophilia Joint Health Score. Participants will complete the physical function tests twice, with a gap of at least 48 hours between sessions. Researchers will monitor performance using these tests to understand their measurement properties. Participants must be adults with hemophilia who can walk independently for 20 meters. The study involves no drugs or medical devices and focuses on gathering reliable data to support better clinical assessments for people living with hemophilia.

Measurement Properties in People with Hemophilia