Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT04468841

Measuring Cell-Free DNA (cfDNA) Levels in People With Follicular Lymphoma

Led by Memorial Sloan Kettering Cancer Center · Updated on 2025-08-19

100

Participants Needed

7

Research Sites

312 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The researchers are doing this study to measure and test cell-free DNA (cfDNA) in the blood before, during, and after first-line treatment for follicular lymphoma. They will look at whether cfDNA levels are related to a person's response to the usual first-line treatment for follicular lymphoma. Researchers also want to understand how different genetic changes in follicular lymphoma relate to a person's response to the usual first-line treatment.

CONDITIONS

Official Title

Measuring Cell-Free DNA (cfDNA) Levels in People With Follicular Lymphoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older at the time of signing informed consent
  • Histology-confirmed follicular lymphoma grade 1-3a verified by the enrolling institution
  • Ability to follow the study visit schedule and protocol requirements
  • Measurable FDG-avid disease
  • Not applicable for retrospective patients in complete remission
Not Eligible

You will not qualify if you...

  • Patients receiving second or greater line of therapy, except retrospective long-term survivors of follicular lymphoma more than 10 years after frontline treatment

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 7 locations

1

Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

Basking Ridge, New Jersey, United States, 07920

Actively Recruiting

2

Memorial Sloan Kettering Monmouth (All protocol activities)

Middletown, New Jersey, United States, 07748

Actively Recruiting

3

Memorial Sloan Kettering Bergen (All protocol Activities)

Montvale, New Jersey, United States, 07645

Actively Recruiting

4

Memorial Sloan Kettering Commack (All Protocol Activities)

Commack, New York, United States, 11725

Actively Recruiting

5

Memorial Sloan Kettering Westchester (All Protocol Activities)

Harrison, New York, United States, 10604

Actively Recruiting

6

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, New York, United States, 10065

Actively Recruiting

7

Memorial Sloan Kettering Nassau (All Protocol Activities)

Uniondale, New York, United States, 11553

Actively Recruiting

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Research Team

P

Paola Ghione, MD

CONTACT

M

Maria Arcila, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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Measuring Cell-Free DNA (cfDNA) Levels in People With Follicular Lymphoma | DecenTrialz