Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07256340

Measuring Total Energy Expenditure in Critically Ill Patients Using the Doubly Labelled Water Method

Led by Maastricht University Medical Center · Updated on 2025-12-10

50

Participants Needed

1

Research Sites

39 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Critically ill patients, such as those with trauma or sepsis, experience high rates of malnutrition (up to 75%). Malnutrition worsens outcomes by increasing infection rates, hospital stays, mortality, and healthcare costs. Adequate nutrition is therefore crucial in the ICU. To ensure appropriate nutrition, accurate determination of total energy expenditure (TEE) is essential. In practice, predictive equations are often used, but these can misestimate TEE in ICU patients due to complex metabolic changes. Indirect calorimetry is recommended but limited by technical constraints. Consequently, the doubly labeled water (DLW) method, though expensive, offers a precise and non-invasive way to measure TEE over time. This study applies the DLW method in ICU patients to improve energy assessment and guide personalized nutrition strategies that support recovery and outcomes.

CONDITIONS

Official Title

Measuring Total Energy Expenditure in Critically Ill Patients Using the Doubly Labelled Water Method

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Admitted to the ICU of Jessa Hospital
  • Male and female sexes
  • Age: > 18 years old
  • Expected ICU stay of 5 days or more
Not Eligible

You will not qualify if you...

  • Receiving dialysis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Jessa Hospital Campus Virga Jesse

Hasselt, Limburg, Belgium, 3500

Actively Recruiting

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Research Team

M

Michèlle Hendriks

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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