Actively Recruiting
Mechanical Bowel Preparation in Laparoscopic Right Hemicolectomy With Intracorporeal Anastomosis
Led by University Medical Center Ho Chi Minh City (UMC) · Updated on 2026-04-22
74
Participants Needed
1
Research Sites
112 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a randomized controlled trial conducted at University Medical Center Ho Chi Minh City to evaluate the role of mechanical bowel preparation (MBP) in patients undergoing laparoscopic right hemicolectomy with totally intracorporeal anastomosis for colon cancer. Mechanical bowel preparation is commonly used before colorectal surgery to reduce bowel contents and potentially decrease the risk of postoperative infections. However, its benefit remains controversial, particularly in intracorporeal anastomosis, where intra-abdominal contamination may influence surgical outcomes. In this study, eligible patients will be randomly assigned to one of two groups: with or without mechanical bowel preparation before surgery. The study aims to compare intraoperative events, postoperative complications, and recovery outcomes between the two groups. The primary outcome is the rate of surgical site infection (SSI) within 30 days after surgery. Secondary outcomes include intraoperative fecal contamination, anastomotic leakage, postoperative ileus, operative time, and recovery parameters such as time to first bowel movement and length of hospital stay. The findings of this study are expected to clarify the role of mechanical bowel preparation in reducing postoperative infections and improving surgical outcomes in patients undergoing laparoscopic right hemicolectomy.
CONDITIONS
Official Title
Mechanical Bowel Preparation in Laparoscopic Right Hemicolectomy With Intracorporeal Anastomosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with colon cancer stage I-III according to the TNM classification
- Patients undergoing elective right hemicolectomy or extended right hemicolectomy with totally intracorporeal anastomosis at University Medical Center Ho Chi Minh City
- Postoperative histopathological confirmation of adenocarcinoma
You will not qualify if you...
- Patients undergoing emergency surgery
- Contraindications to mechanical bowel preparation such as bowel obstruction, subobstruction, bowel perforation, or peritumoral abscess
- Contraindications to laparoscopic surgery (American Society of Anesthesiologists [ASA] physical status IV or V) or intracorporeal anastomosis
- Presence of distant metastasis at the time of surgery (stage IV according to the TNM classification)
- Recurrent colon cancer after prior surgery
- Synchronous primary malignancies in other organs
- Patients undergoing palliative surgery or surgery for tumor-related complications with non-curative intent
- Inability to complete follow-up or be contacted
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Trial Site Locations
Total: 1 location
1
University Medical Center HCMC
Ho Chi Minh City, Ho Chi Minh, Vietnam, 70000
Actively Recruiting
Research Team
T
Tran D Huy, PhD, MD
CONTACT
L
Le M Triet, MD,
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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