Actively Recruiting
Mechanical Ventilation on Hippocampus
Led by Beijing Sanbo Brain Hospital · Updated on 2024-08-09
20
Participants Needed
1
Research Sites
55 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Ventilator-associated brain injury (VABI) frequently occurs in ICU patients. Although animal studies indicate the hippocampus as a key target of VABI, its relevance in human patients remains uncertain. In this study, the investigators aim to monitor hippocampal EEG activity during the weaning process of patients off mechanical ventilation, and also exploring the coupling between breathing patterns and hippocampal activity.
CONDITIONS
Official Title
Mechanical Ventilation on Hippocampus
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- ASA classification I - II
- Have at least one electrode contact inside the hippocampus
- Signed informed consent form
You will not qualify if you...
- Seizure occurrence within 36 hours before the operation
- Structural brain damage
- History of using opioids, enzyme-inducing medications, sleep aids, or excessive alcohol consumption
- History of mechanical ventilation lasting more than 24 hours
- Cognitive impairment
- Surgery within the last 6 months
- Participation in other clinical trials within the last four weeks
- Pregnant or breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Beijing Sanbo Brain Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100090
Actively Recruiting
Research Team
Z
Zhonghua Shi, PhD,MD
CONTACT
X
Xiang Qi
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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