Actively Recruiting

All Genders
NCT06367946

Mechanism Study of Ventilator-Induced Lung Injury in Elderly People.

Led by Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · Updated on 2024-04-16

1000

Participants Needed

1

Research Sites

212 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

1. We collect lung tissues from patients with different ages and confirm that KLK8 expression is positively correlated with age. 2. We collect peripheral blood from patients with different ages and duration of mechanical ventilation to explore the correlation between the degree of endothelial/epithelial damage, age and duration of mechanical ventilation.

CONDITIONS

Official Title

Mechanism Study of Ventilator-Induced Lung Injury in Elderly People.

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing elective general anesthesia surgery
  • Patients undergoing partial lung resection with mechanical ventilation
  • American Society of Anesthesiology (ASA) grade 2-3
  • Patients undergoing elective general anesthesia surgery with mechanical ventilation
  • American Society of Anesthesiology (ASA) grade 2-3
Not Eligible

You will not qualify if you...

  • Patients with chronic lung diseases such as asthma, COPD, or pulmonary heart disease
  • Patients with HIV, hepatitis B, hepatitis C, hepatitis D, or receiving immunotherapy
  • Patients who have recently suffered from pneumonia
  • Patients with recent history of mechanical ventilation
  • Patients with thrombotic diseases
  • Children and pregnant women
  • Smoking patients
  • Patients with hypertension, diabetes, or coronary heart disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Shanghai Xinhua hospital

Shanghai, China, 200000

Actively Recruiting

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Research Team

L

Lai Jiang, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

6

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