Actively Recruiting
Mechanisms of Anabolic Resistance in Older Humans
Led by Mayo Clinic · Updated on 2026-01-21
120
Participants Needed
1
Research Sites
295 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this research is to understand how chronic inflammation affects muscle function and responses to exercise in older adults.
CONDITIONS
Official Title
Mechanisms of Anabolic Resistance in Older Humans
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 21 to 85 years
You will not qualify if you...
- Diabetes or fasting plasma glucose of 126 mg/dL or higher
- Body mass index (BMI) of 30 kg/m2 or higher
- Anemia (hemoglobin less than 11 g/dl for females and less than 12 g/dl for males)
- Active coronary artery disease or recent (within 3 months) unstable macrovascular events such as unstable angina, myocardial infarction, stroke, or revascularization
- Renal failure with serum creatinine greater than 1.5 mg/dl
- Chronic active liver disease (AST greater than 144 IU/L or ALT greater than 165 IU/L)
- Use of oral warfarin or history of blood clotting disorders
- Smoking
- Pregnancy or breastfeeding
- Alcohol consumption greater than 2 glasses per day or other substance abuse
- Untreated or uncontrolled hypothyroidism
- Debilitating chronic disease as determined by investigators
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
R
Rachel Passehl
CONTACT
I
Ian Lanza
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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