Actively Recruiting
Mechanisms and Factors Responsible for the Inhibition of Transposons During Fetal Gonad Development in Humans
Led by Centre Hospitalier Universitaire Dijon · Updated on 2022-07-08
30
Participants Needed
1
Research Sites
674 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a single-centre study over 36 months for the inclusion of 30 patients. The selection and inclusion of patients will take place according to the criterion of Medical Termination of Pregnancy at 4 different gestational ages (8-12 weeks of gestation (WG)), 13-16 WG, 17-23 WG and 25-35 WG. The tissue analysed will principally be the gonads, other somatic tissue will also be systematically harvested in parallel (liver and psoas muscle) for control purposes. The gonads will be subjected to molecular biology analyses destined to quantify the expression of transposons and their inhibitors.
CONDITIONS
Official Title
Mechanisms and Factors Responsible for the Inhibition of Transposons During Fetal Gonad Development in Humans
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Couple or mother who has provided written informed consent
- Fetus between 10 and 37 weeks of amenorrhea
- Male fetus
- Fetus obtained following medical termination of pregnancy or voluntary termination of pregnancy
You will not qualify if you...
- Persons without national health insurance cover
- Fetus presenting aneuploidy
- Fetus presenting a malformation of the genital organs
AI-Screening
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Trial Site Locations
Total: 1 location
1
CHU de DIJON
Dijon, France, 21079
Actively Recruiting
Research Team
P
Patricia FAUQUE
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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