Actively Recruiting
Mechanisms of Improving Fecal Continence Muscles Motor Function
Led by Medical College of Wisconsin · Updated on 2025-10-23
340
Participants Needed
1
Research Sites
241 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The investigators hypothesize that different continence muscles have different fatigue characteristics and fatigue induced by resisted contractions will result in significant increase in contractility of the continence muscles and improvement of fecal incontinence severity.
CONDITIONS
Official Title
Mechanisms of Improving Fecal Continence Muscles Motor Function
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy volunteers without past or present history of fecal incontinence
- Patients age 18 years and older with reduced anal resting and/or squeeze pressure who can perform the study
You will not qualify if you...
- Any one less than 18 years old
- Neurological disorders like dementia, cerebrovascular diseases
- Muscle diseases like muscular dystrophy, myopathies
- Inflammatory bowel disease or celiac disease
- Neuro-muscular junction disorders/myasthenia gravis, Eaton-Lambert syndrome
- Organ prolapse, large rectocele (>2cm), rectal intussusception
- Hip dysplasia or recent hip surgery and immobile patients
- Patients with complete normal anal resting and squeeze pressure
- Impaired rectal evacuation (dyssynergy defecation)
- Fecal incontinence completely due to loss of rectal sensation
- Subjects unable to contract their external anal sphincter at all
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53086
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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