Actively Recruiting

Age: 18Years +
FEMALE
NCT07297394

Mechanisms of Maternal Immune Tolerance in Early Pregnancy

Led by University Hospital, Basel, Switzerland · Updated on 2026-03-04

100

Participants Needed

1

Research Sites

247 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study explores the mechanisms of maternal immune tolerance in early pregnancy by characterizing immune cell profiles and functional pathways during the first trimester. The goal is to identify immunological factors that support healthy gestation and prevent complications such as miscarriages.

CONDITIONS

Official Title

Mechanisms of Maternal Immune Tolerance in Early Pregnancy

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Blood will be collected before and during pregnancies or failed implantation conceived through IVF/ICSI treatment and in case of miscarriage
  • Participant is 18 years of age or older
  • Participant has signed a written informed consent
Not Eligible

You will not qualify if you...

  • Presence of certain maternal infections: HIV, Hepatitis B, Hepatitis C, or Syphilis
  • Use of immunosuppressive medications at the time of blood sample collection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital Basel

Basel, Switzerland, 4031

Actively Recruiting

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Research Team

U

Ursula Gobrecht-Keller, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Mechanisms of Maternal Immune Tolerance in Early Pregnancy | DecenTrialz