Actively Recruiting
Mechanisms and Modulation of Pain Modulatory Capacity
Led by University of Florida · Updated on 2026-01-20
180
Participants Needed
1
Research Sites
282 weeks
Total Duration
On this page
Sponsors
U
University of Florida
Lead Sponsor
N
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This project proposes to understand the sources of pain variability, and demonstrate that pain variability represents fluctuation in natural pain management. The project further proposes to determine if endogenous capacity to modulate pain can be trained to maximize their body's ability to manage pain, much as the way in which athletic performance can be trained.
CONDITIONS
Official Title
Mechanisms and Modulation of Pain Modulatory Capacity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Asymptomatic people with no current pain conditions
- Participants with widespread muscle pain aged 18 years and older
- Participants with widespread muscle pain must meet the ACR (2010) diagnostic criteria
- Asymptomatic participants must have no current wrist/hand, elbow, or shoulder pain
- Asymptomatic participants must have no chronic pain conditions such as irritable bowel syndrome or fibromyalgia
You will not qualify if you...
- Participation in a biceps-specific conditioning program in the past 6 months
- Wrist, hand, elbow, or shoulder pain reported in the last 3 months
- Chronic medical conditions affecting pain perception (e.g., diabetes, high blood pressure), kidney dysfunction, muscle damage, or major psychiatric disorder
- Use of any interventions for pain symptoms induced by training during the study
- Positive pre-MRI metal screening or pregnancy test
- Presence of ferromagnetic metal in the head, neck, or abdominal cavity
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Unversity of Florida
Gainesville, Florida, United States, 32611
Actively Recruiting
Research Team
M
Mark D Bishop, PhD
CONTACT
J
Jeff Boissoneault, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
3
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