Actively Recruiting
Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)
Led by Johns Hopkins University · Updated on 2026-03-09
140
Participants Needed
3
Research Sites
260 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins University
Lead Sponsor
E
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The researchers are evaluating mechanisms of uterine fluid absorption during early pregnancy
CONDITIONS
Official Title
Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy women between 18 and 45 years old
- Women diagnosed with endometriosis or infertility (cases)
- Women without endometriosis or infertility (controls)
- Regular menstrual cycles
- Body mass index (BMI) between 18 and 40
- Sexually active or previously had a vaginal exam using a speculum
- Able to understand and give consent for procedures and use of health information
- No history of Chlamydia trachomatis, Mycoplasma genitalium, Neisseria gonorrhoeae, hepatitis B, or HIV
- For IVF subjects, minimum endometrial thickness of 7mm at sample collection
You will not qualify if you...
- Pregnant women
- Women with endometrial cancer
- Women with a history of endometrial ablation
- Women with undiagnosed uterine bleeding
- Women with reproductive diseases affecting the endometrium, such as fibroids or uterine polyps that distort the uterine cavity
- Women with an intrauterine device (IUD)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
University of Georgia
Athens, Georgia, United States, 30602
Not Yet Recruiting
2
Johns Hopkins Hospital
Baltimore, Maryland, United States, 21287
Actively Recruiting
3
Rutgers University
Piscataway, New Jersey, United States, 08854
Active, Not Recruiting
Research Team
J
James Segars, MD
CONTACT
B
Bhuchitra Singh, MD, MPH, MS, MBA
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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