Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT04670640

Mechanistic Interventions and Neuroscience of Dissociation

Led by Emory University · Updated on 2026-04-20

350

Participants Needed

2

Research Sites

284 weeks

Total Duration

On this page

Sponsors

E

Emory University

Lead Sponsor

N

National Center for Complementary and Integrative Health (NCCIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to test the neurophysiological mechanisms of an intervention to reduce symptoms of dissociation in traumatized people. The intervention will be tested in dissociative traumatized people at two sites: Emory University and University of Pittsburgh. The researchers are interested in whether neural networks associated with attentional control and interoceptive awareness can be enhanced in this population. The researchers propose to evaluate whether different body-focused and non-body focused interventions can change these mechanisms.

CONDITIONS

Official Title

Mechanistic Interventions and Neuroscience of Dissociation

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Experience at least one DSM-5 Criterion A trauma (assessed by Life Events Checklist)
  • Score 7 or higher on the Multiscale Dissociation Inventory depersonalization subscale
  • Willingness to participate in the study
Not Eligible

You will not qualify if you...

  • Actively psychotic or cognitively compromised (assessed by MoCA)
  • Moderate or more severe substance dependence (assessed with MINI)
  • Imminent risk of physical violence to self or others

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Grady Hospital

Atlanta, Georgia, United States, 30303

Actively Recruiting

2

Western Psychiatric Institute and Clinic

Pittsburgh, Pennsylvania, United States, 15213

Completed

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Research Team

N

Negar Fani, PhD

CONTACT

G

Greg Siegle, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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Mechanistic Interventions and Neuroscience of Dissociation | DecenTrialz