Actively Recruiting
A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol
Led by Marea Therapeutics · Updated on 2025-11-06
30
Participants Needed
1
Research Sites
57 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary objective of the study is to determine the effect of MAR001 as compared to placebo on levels of the triglycerides (TG) in the postprandial state in adults with elevated TG.
CONDITIONS
Official Title
A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Willingness to provide informed consent and comply with the intervention and all study assessments
- Two fasting triglyceride tests collected at two separate, consecutive visits at least 7 days apart during screening
- HbA1c between 5.7% and 8.5%
- Stable diet for at least 3 months before screening with no plans to change during the study
- Stable drug regimen before screening with no planned changes during screening or trial participation
You will not qualify if you...
- Acute or chronic liver disease
- Use of diabetes medications other than metformin
- History of type 1 diabetes mellitus or diabetic ketoacidosis
- Newly diagnosed type 2 diabetes mellitus
- Known active hepatitis A, B, or C infection
- Known uncontrolled HIV infection
- Uncontrolled hypothyroidism
- Any condition preventing compliance with study procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Marea Site 301
Chula Vista, California, United States, 91911
Actively Recruiting
Research Team
A
Andrew Lane
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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